DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and Lims2

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001366066.1	Gene:	Lims2 / 225341	MGIID:	2385067	Length:	341	Species:	Mus musculus

Alignment Length:	239	Identity:	80/239 - (33%)
Similarity:	119/239 - (49%)	Gaps:	9/239 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   347 CCNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPR----- 406
            ||..|.:.::|:||.|:...|||..|.|..|..||....|.:..|...|.| .||....:
Mouse    75 CCGFCGEFVIGRVIKAMNANWHPGCFRCELCDVELADLGFVKNAGRHLCRP-CHNREKAKGLGKF 138

  Fly   407 -CAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCN 470
             |..|:.||.::.:...:..:|.:||.|:.||::...:. .|..|:.||...:.:|..|.|..|.
Mouse   139 ICQRCHLAIDEQPLMFKNDPYHPDHFSCSNCGKELTSDA-RELKGELYCLPCHDKMGIPICGACR 202

  Fly   471 RAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGCSKPITGR 535
            |.|....::||..|||.:.|||..|.:||.|...::.:||.||||||:...|.:|..||..|.|.
Mouse   203 RPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGD 267

  Fly   536 CITAMFKKFHPEHFVCAFC-LKQLNKGTFKEQKDKPYCHTCFDK 578
            .::|:.|.:....|.|:.| :|...|..|.|...||.|..|:::
Mouse   268 VVSALSKAWCVNCFSCSTCNMKLTLKNKFVEFDMKPVCKRCYER 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	18/51 (35%)
		LIM2_Paxillin_like	407..458	CDD:188723	14/50 (28%)
		LIM3_Paxillin_like	466..518	CDD:188724	23/51 (45%)
		LIM4_Paxillin	525..576	CDD:188795	17/51 (33%)
Lims2	NP_001366066.1	LIM1_PINCH	15..73	CDD:188717
		LIM2_PINCH	76..127	CDD:188718	18/51 (35%)
		LIM3_PINCH	140..190	CDD:188719	14/50 (28%)
		LIM4_PINCH	196..249	CDD:188720	23/52 (44%)
		LIM5_PINCH	257..310	CDD:188721	18/52 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920