DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and C34B2.4

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_492793.1	Gene:	C34B2.4 / 183192	WormBaseID:	WBGene00016389	Length:	131	Species:	Caenorhabditis elegans

Alignment Length:	166	Identity:	45/166 - (27%)
Similarity:	57/166 - (34%)	Gaps:	65/166 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   348 CNACEKPIVGQ--VITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYC 410
            |..|...| |:  .|.|.||.||..|..|:.|...:       .||             .||...
Worm     4 CGHCSVKI-GEESAILANGKVWHVNHLLCDLCKCRI-------NDG-------------ERCVPQ 47

  Fly   411 NGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNRAIME 475
            ||.||                 |::|         |.:..:|.|:            ||...|..
Worm    48 NGVIL-----------------CSEC---------HIKTTRPICK------------GCGEFIKT 74

  Fly   476 NYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLP 511
            |:..||||.|||.||.|..|::|.:    .|...||
Worm    75 NFCEALNSTWHPTCFQCSVCQKPLK----VDFHQLP 106

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	15/53 (28%)
		LIM2_Paxillin_like	407..458	CDD:188723	10/50 (20%)
		LIM3_Paxillin_like	466..518	CDD:188724	19/46 (41%)
		LIM4_Paxillin	525..576	CDD:188795
C34B2.4	NP_492793.1	LIM	4..57	CDD:259829	23/99 (23%)
C34B2.4	NP_492793.1	LIM	65..>97	CDD:295319	16/43 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810