DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and lim-4

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_508669.1	Gene:	lim-4 / 180672	WormBaseID:	WBGene00002987	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	241	Identity:	56/241 - (23%)
Similarity:	87/241 - (36%)	Gaps:	48/241 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 AHLTQTIEETTIVEDSREDQLDSMLGNLQANMSRQGVNTVQKGCCNACEKPIVGQVITALGKTWH 368
            |||.|..:.:|..|.|........:|:..::.|....:.| ..|.|          :|..|....
Worm     3 AHLVQAKKTSTASELSDSSLTFPFIGDYLSSPSLTTSDYV-SDCSN----------LTVEGPVPA 56

  Fly   369 PEHFTCN-----HCSQELGTRNF-FERDGFPYCEPDYHNLFSPRCAYCNGAILDKCVTALD-KTW 426
            .:.|:.:     :.|..|...:: |..|.....:||...:.   |..|...|.||...::| :.:
Worm    57 NQEFSSSDESSVYISSALRLADYAFTPDDNIRIKPDAVIVI---CTQCQHQIQDKFFLSIDGRNY 118

  Fly   427 HTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEM-----------FAPKCNGCNRAIM------ 474
            |.....|:.|......:.|: :|...||:..||..           ..|||..|:|.|.
Worm   119 HENCLQCSTCENPLSNKCFY-KDKTFYCKGCYFRTHVTSTASSCRELGPKCASCDRTIQATDWVR 182

  Fly   475 --ENYISALNSQWHPDCFVCRDC-RQPFQGGSFFDHEGLPYCETHY 517
              .||:      :|..||.|..| ||...|..:...||...|:.|:
Worm   183 RARNYV------YHLACFSCNQCKRQLSTGEEYALQEGNLLCKQHF 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	10/57 (18%)
		LIM2_Paxillin_like	407..458	CDD:188723	13/51 (25%)
		LIM3_Paxillin_like	466..518	CDD:188724	18/61 (30%)
		LIM4_Paxillin	525..576	CDD:188795
lim-4	NP_508669.1	LIM	98..153	CDD:278823	15/55 (27%)
		LIM2_AWH	168..222	CDD:188765	17/59 (29%)
		HOX	239..295	CDD:197696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910