DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and tes-1

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_501190.1	Gene:	tes-1 / 177515	WormBaseID:	WBGene00015217	Length:	465	Species:	Caenorhabditis elegans

Alignment Length:	404	Identity:	93/404 - (23%)
Similarity:	149/404 - (36%)	Gaps:	80/404 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 HIYAVPNGSAHKSPTPGRHVTITVRETKTEKLTGPDGPVGTVEEQIVQQKDSYTPNHAVPGQQVH 243
            |...:||...|.....||  ....||...:.||.|               ..|.||.....::.:
Worm    72 HDVVLPNEFDHAQIVIGR--LFGAREHFEKVLTKP---------------GMYKPNEQNETKENN 119

  Fly   244 QAYT-SQATKELDDLMASLSDFKVSNGTNGIGNGSH-----PQQHSSTVQHQTVTDYARP---NK 299
            ...| ||.|...:..|||........|:|...|..:     |.::..:...:.:.:..||   :|
Worm   120 MMSTRSQPTAVYNYKMASSDSESERGGSNNKENVQYAWAPLPDKNLVSRYMKALPEDERPLVGSK 184

  Fly   300 GSQ--------QAHLTQ-TIEETTIVEDSREDQLDSMLGNLQANM-----------------SRQ 338
            |.|        |..|.. .:|:...||:.....|.:.:.|::.|:                 ..:
Worm   185 GEQNRKSRLQFQLPLYDCNVEDARFVEEKDVKTLQNFVENVRNNVIGVGRVVEIGKDSDNYGDNE 249

  Fly   339 GVNTVQKGC-------------CNACEKPI-VGQVIT-----ALGKTWHPEHFTCNHCSQELGTR 384
            ..|..:|..             |..|.:.: .|.:..     :...|:||..|.|..|.|.|...
Worm   250 NTNEFEKSMTAALKGLKIGETDCKDCNEMMETGDIGVECHHHSTTDTYHPNCFRCETCRQLLVDN 314

  Fly   385 NFFERDGFPYCEPDYHNLFSPRCAYCNGAIL-DKCVTALDKTWHTEHFFCAQCGQQFGEEGFHER 448
            .:|......||...|.:...||||.|:..|. ::...|.:|:||.:||.|.:|..:.|...:..|
Worm   315 IYFFYKNKYYCGRHYADQLYPRCAGCDELIFANEYTFAEEKSWHFDHFACYKCDFKLGGSRYMTR 379

  Fly   449 DGKPYCRNDYFEMFAPKCNGCNRAI--MENYISALNSQWHPD--CFVCRDCRQPFQGGSFF--DH 507
            |..|:|.:.|.:.||..|:.|...|  .|..::...:.||.:  ||.|..|:....|..|.  :|
Worm   380 DENPFCLDCYLKHFAKTCDTCQSKIGPDEKRLNYNETHWHAEERCFQCVQCKMNLIGKKFMLKNH 444

  Fly   508 EGL--PYCETHYHA 519
            :.|  ..|:.:|::
Worm   445 KLLCSSQCKANYNS 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	14/57 (25%)
		LIM2_Paxillin_like	407..458	CDD:188723	17/51 (33%)
		LIM3_Paxillin_like	466..518	CDD:188724	15/59 (25%)
		LIM4_Paxillin	525..576	CDD:188795
tes-1	NP_501190.1	PET_testin	153..239	CDD:193604	14/85 (16%)
		LIM1_Testin_like	272..329	CDD:188726	14/56 (25%)
		LIM2_Testin_like	335..389	CDD:188727	19/53 (36%)
		LIM3_Testin_like	397..453	CDD:188728	14/55 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910