Protein Alignment Pax and pxl-1

DIOPT Version :9

• Sequence 1: NP_001033913.1
• Gene: Pax / 35215
• FlyBaseID: FBgn0041789
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001021185.2
• Gene: pxl-1 / 175831
• WormBaseID: WBGene00016197
• Length: 413
• Species: Caenorhabditis elegans
• Alignment Length: 454
• Identity: 178/454 - (39%)
• Similarity: 245/454 - (53%)
• Gaps: 95/454 - (20%)

  Fly   165 RPSVDSLLKELDNAHIYAVPNGSAHKSPTPGRHVTITVRETKTEKLTGPDGPVGTVEEQIVQQKD 229
            :|::::||.:|                    :|.|..:|...             :.::..|.:|
 Worm    12 KPALEALLSDL--------------------QHTTEVLRRAH-------------ISDRRSQSRD 43

  Fly   230 SYTPNHAVPGQQVHQAYTSQATKELDDLMASLSDFKVSNG---TNGIGNGSHPQQHSSTVQHQTV 291
            .:           .|:|         ||..:|:...||||   |:.....|...:..|..|.:..
 Worm    44 DF-----------EQSY---------DLQGNLNTQSVSNGNITTSPYKRRSSEGKDYSKSQERIY 88

  Fly   292 TD--------YARPNKGSQQAHLTQTIEETTIVEDSREDQL------------------------ 324
            .:        |:||   |.|:.|:| :||..|...|....|
 Worm    89 ENESRLNPPVYSRP---SVQSLLSQ-VEEPPIRASSSRKSLGPPSQAQSYSDVRSNGRSPSRDPL 149

  Fly   325 --DSMLGNLQANM-SRQGVNTVQKGCCNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNF 386
              |||:|.:...: |:.||||:.||.|.||.|||:|||:.||||.|||||:||..|..|||.|.|
 Worm   150 HSDSMIGTMNGELSSKHGVNTIPKGDCAACGKPIIGQVVIALGKMWHPEHYTCCECGAELGQRPF 214

  Fly   387 FERDGFPYCEPDYHNLFSPRCAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGK 451
            |||:|..:||.||||.|||:|..|:.||.|:||:.::|.:|.|.|.||:|.|.|||:||||::|:
 Worm   215 FERNGRAFCEEDYHNQFSPKCQGCHRAITDRCVSVMNKNFHIECFTCAECNQPFGEDGFHEKNGQ 279

  Fly   452 PYCRNDYFEMFAPKCNGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETH 516
            .||:.|:|.:||||||||::.|..|:|:||.:.||||||||:.|...|.|.|||:|.|.|.||.|
 Worm   280 TYCKRDFFRLFAPKCNGCSQPITSNFITALGTHWHPDCFVCQHCGVSFNGASFFEHNGAPLCERH 344

  Fly   517 YHAKRGSLCAGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKDKPYCHTCFDKIF 580
            ||..|||:|:.|...|.|||:.||.:|||||||.|::|..||.||||||...:|:||.|::..:
 Worm   345 YHESRGSICSQCRGAINGRCVAAMGRKFHPEHFRCSYCNHQLTKGTFKEVDRRPFCHKCYNNTY 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	33/51 (65%)
		LIM2_Paxillin_like	407..458	CDD:188723	25/50 (50%)
		LIM3_Paxillin_like	466..518	CDD:188724	29/51 (57%)
		LIM4_Paxillin	525..576	CDD:188795	28/50 (56%)
pxl-1	NP_001021185.2	LIM1_Leupaxin	174..228	CDD:188790	34/53 (64%)
		LIM	235..290	CDD:278823	27/54 (50%)
		LIM3_Paxillin_like	294..346	CDD:188724	29/51 (57%)
		LIM4_Paxillin_like	353..404	CDD:188725	28/50 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162491
Domainoid	1	1.000	89	1.000	Domainoid score	I5022
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H136149
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	1	1.000	-	-		oto17816
orthoMCL	1	0.900	-	-		OOG6_104097
Panther	1	1.100	-	-	LDO	PTHR24216
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1093
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.880