DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pax and Y1A5A.1

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_497801.1	Gene:	Y1A5A.1 / 175515	WormBaseID:	WBGene00012379	Length:	192	Species:	Caenorhabditis elegans

Alignment Length:	179	Identity:	49/179 - (27%)
Similarity:	84/179 - (46%)	Gaps:	20/179 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 PIVGQVITALGKTWHPEHFTCN-HCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYCNGAILDK 417
            |::.|.|    ..:||:..||. ..|:.:.|..|:..     |:....::....|.:|:.:|..:
Worm    22 PLLCQYI----PRYHPQMPTCPLFESKSIITPVFYFN-----CKRMDRSIDRRLCGHCHQSIGSE 77

  Fly   418 CVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNRAIMENYISALN 482
            .:.|:::.||.:||.|:.|.:.. ::.|...|...||...:.:.:.|||.||...:::..:.||:
Worm    78 ALVAMNRLWHPDHFTCSSCKRPI-KQTFQAADNHAYCVQCFAQKYNPKCAGCMETLVDTCLLALD 141

  Fly   483 SQWHPDCFVCRDCRQPFQGGSFFDHEGLPY---C------ETHYHAKRG 522
            ..|||.||.|..|.:|...|.|:..:..||   |      |...|.:||
Worm   142 RHWHPRCFTCSSCNRPLPNGEFYLVDDKPYDLDCHWAKRLEKREHMERG 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	11/46 (24%)
		LIM2_Paxillin_like	407..458	CDD:188723	14/50 (28%)
		LIM3_Paxillin_like	466..518	CDD:188724	19/60 (32%)
		LIM4_Paxillin	525..576	CDD:188795
Y1A5A.1	NP_497801.1	LIM	67..117	CDD:295319	14/50 (28%)
Y1A5A.1	NP_497801.1	LIM_DA1	125..176	CDD:188782	17/50 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820