DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pax and Lhx3

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_038962056.1	Gene:	Lhx3 / 170671	RGDID:	71078	Length:	416	Species:	Rattus norvegicus

Alignment Length:	141	Identity:	46/141 - (32%)
Similarity:	65/141 - (46%)	Gaps:	9/141 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   405 PRCAYCNGAILDKCV-TALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNG 468
            |.||.|:..|||:.: .|||:.||::...|:.|.....|..| .|....||::|:|:.|..||..
  Rat    19 PMCAGCDQHILDRFILKALDRHWHSKCLKCSDCHVPLAERCF-SRGESVYCKDDFFKRFGTKCAA 82

  Fly   469 CNRAIMENYI--SALNSQWHPDCFVCRDC-RQPFQGGSFF-DHEGLPYCETHYH-AKRGSLCAGC 528
            |...|....:  .|.:..:|..||.|..| ||...|..|: ..:....|:..|. ||:....|..
  Rat    83 CQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATA 147

  Fly   529 SKPITGRCITA 539
            .:|.|  .|||
  Rat   148 KRPRT--TITA 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830
		LIM2_Paxillin_like	407..458	CDD:188723	18/51 (35%)
		LIM3_Paxillin_like	466..518	CDD:188724	14/55 (25%)
		LIM4_Paxillin	525..576	CDD:188795	6/15 (40%)
Lhx3	XP_038962056.1	LIM1_Lhx3b	18..72	CDD:188851	19/53 (36%)
		LIM2_Lhx3_Lhx4	80..135	CDD:188762	14/54 (26%)
		Homeobox	150..233	CDD:395001	5/9 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910