DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and AgaP_AGAP008979

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_319729.4	Gene:	AgaP_AGAP008979 / 1279942	VectorBaseID:	AGAP008979	Length:	271	Species:	Anopheles gambiae

Alignment Length:	184	Identity:	49/184 - (26%)
Similarity:	66/184 - (35%)	Gaps:	50/184 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 CNHCSQELGT----RNFFERDGFPYCEPDYHNLFS-PRCAYCNGAI--LDKCVTALDKTWHTEHF 431
            |..|.:.|.|    .:.:.|:|..||:.||:..|| .|||.|...|  .|..:.|.|..:|...|
Mosquito     3 CLRCCKCLHTLEAELSCYSREGNIYCKDDYYRHFSVRRCARCGNGISASDLVMRAKDLIFHVNCF 67

  Fly   432 FCAQCGQQF-GEEGFHERDGKPYC---RNDYFEMFAPKCNGCNRAIMENYISALNSQ-----WHP 487
            .|..|||.. |.:....|||:.:|   ..:......|...|.|....::....|..|     ||
Mosquito    68 SCLICGQLLRGGDTAGIRDGRVFCGKLPTNRARRQTPNRGGANPPGRQSTHGLLPGQVCHLLWH- 131

  Fly   488 DCFVCRDCRQPFQGGSFFDHEGLP-----------YCETHYHAKRGSLCAGCSK 530
                             |:|..:|           ||     ||.|||...|.:
Mosquito   132 -----------------FNHVSIPGAHIRSPPRWNYC-----AKDGSLHCDCRR 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	9/29 (31%)
		LIM2_Paxillin_like	407..458	CDD:188723	18/56 (32%)
		LIM3_Paxillin_like	466..518	CDD:188724	11/67 (16%)
		LIM4_Paxillin	525..576	CDD:188795	1/6 (17%)
AgaP_AGAP008979	XP_319729.4	LIM	<1..32	CDD:295319	8/28 (29%)
		LIM	37..91	CDD:295319	19/53 (36%)
		HOX	224..270	CDD:197696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910