DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and AgaP_AGAP010209

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_319393.4	Gene:	AgaP_AGAP010209 / 1279631	VectorBaseID:	AGAP010209	Length:	451	Species:	Anopheles gambiae

Alignment Length:	136	Identity:	47/136 - (34%)
Similarity:	63/136 - (46%)	Gaps:	13/136 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   407 CAYCNGAILDKCV--TALDKTWHTEHFFCAQCGQQFGEEG--FHERDGKPYCRNDYFEMFAPKCN 467
            |..|.|.|.|:.:  .|.|..||.....|.:| :||.:|.  ...||||.||:.||..:|..||:
Mosquito    56 CVGCGGQIHDQYILRVAPDLEWHAACLKCQEC-RQFLDESCTCFVRDGKTYCKRDYVRLFGTKCD 119

  Fly   468 GCNRAIMEN--YISALNSQWHPDCFVCRDC-RQPFQGGSFFDHE-GLPYC-ETHYHAKRGS---L 524
            .|..:..:|  .:.|....:|.:||.|..| ||...|..|...: |..|| |.|.|.::.|   |
Mosquito   120 KCGSSFSKNDFVMRAKTKIYHIECFRCSACARQLIPGDEFALRDGGSLYCKEDHDHLEKSSQNGL 184

  Fly   525 CAGCSK 530
            ..|..|
Mosquito   185 VQGAGK 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830
		LIM2_Paxillin_like	407..458	CDD:188723	20/54 (37%)
		LIM3_Paxillin_like	466..518	CDD:188724	18/56 (32%)
		LIM4_Paxillin	525..576	CDD:188795	2/6 (33%)
AgaP_AGAP010209	XP_319393.4	LIM1_Isl	56..110	CDD:188752	20/54 (37%)
		LIM2_Isl	118..173	CDD:188760	17/54 (31%)
		COG5576	196..>318	CDD:227863
		HOX	244..300	CDD:197696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910