Protein Alignment Pax and AgaP_AGAP008532

DIOPT Version :9

• Sequence 1: NP_001033913.1
• Gene: Pax / 35215
• FlyBaseID: FBgn0041789
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_316909.4
• Gene: AgaP_AGAP008532 / 1277441
• VectorBaseID: AGAP008532
• Length: 596
• Species: Anopheles gambiae
• Alignment Length: 621
• Identity: 397/621 - (63%)
• Similarity: 436/621 - (70%)
• Gaps: 65/621 - (10%)

  Fly     1 MDRTMYGKIDPGARQPYR-TARSKGILPGYALLADLQNSVPGQPQQPQPQYGTVQPKHQALQQQQ 64
            ||||.|||.||||||||| |.|.:||.|||||||||||:|||..||.....|
Mosquito     1 MDRTCYGKFDPGARQPYRCTLRDRGIAPGYALLADLQNTVPGHNQQQHGGGG------------- 52

  Fly    65 FVDNTPGYGSLRG-----KAQP-----------QVYQEHYSVETRSPTAGHDFNGS---STTPGY 110
             ..:.||||||.|     :..|           |.||...:.......|.:.:|||   ||||
Mosquito    53 -ASSVPGYGSLNGVRNKQQTSPVPVRIRHLRGCQTYQNTTAKTVTESRATNGYNGSLPRSTTP-- 114

  Fly   111 ANQGSLPRQA------AGASTGLSELDSLLQDLQKIDVPVNYSTPVSKYNTMNSYA---TVEERP 166
              ..||||.:      ..||..|||||||||||..    ..|.....|..:..:.|   :..:||
Mosquito   115 --HNSLPRSSTPQKLQTSASGNLSELDSLLQDLSS----ARYGNVAEKRKSAPTCAVRVSRIKRP 173

  Fly   167 SVDSLLKELDNAH---IYAVPNGSAHKSPTPGRHVTITVRETKTEKLTGPDG---PVGTVEEQIV 225
            ||||||:||.|||   |||||:|:.:.: .|||.||||||||.||||||...   ||..:.....
Mosquito   174 SVDSLLEELSNAHSNPIYAVPHGNQNAN-QPGRQVTITVRETTTEKLTGTPSAHHPVAKLHSLHY 237

  Fly   226 QQKDSYTPNHAVPGQQVHQAYTSQATKELDDLMASLSDFKVSNGTNGIGNGSHPQQHS--STVQH 288
            .:..|..|.|.......::::||.|||||||||||||||||....|.||. ....:||  |...|
Mosquito   238 MRLQSMQPAHQDTTLAQNESHTSSATKELDDLMASLSDFKVICALNSIGT-LQQMKHSFASVNPH 301

  Fly   289 QTVTDYAR-PNKGSQ--QAHLTQTIEETTIVEDSREDQLDSMLGNLQANMSRQGVNTVQKGCCNA 350
            ..:...|. ||:|:.  |:.|| |:..|..:..:..||||||||||.|:||||||||.|||||||
Mosquito   302 SCICTLALCPNQGTSHYQSTLT-TVSTTEHLPPASSDQLDSMLGNLTADMSRQGVNTTQKGCCNA 365

  Fly   351 CEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYCNGAIL 415
            |:|||||||||||||||||||||||||:|||||||||||||.||||||||||||||||||||.||
Mosquito   366 CDKPIVGQVITALGKTWHPEHFTCNHCNQELGTRNFFERDGNPYCEPDYHNLFSPRCAYCNGPIL 430

  Fly   416 DKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNRAIMENYISA 480
            |||||||:|||||||||||||||||||:||||||||||||||||:||||||||||||||||||||
Mosquito   431 DKCVTALEKTWHTEHFFCAQCGQQFGEDGFHERDGKPYCRNDYFDMFAPKCNGCNRAIMENYISA 495

  Fly   481 LNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGCSKPITGRCITAMFKKFH 545
            ||||||||||||||||:||.|||||||||||||||||||||||||||||||||||||||||||||
Mosquito   496 LNSQWHPDCFVCRDCREPFHGGSFFDHEGLPYCETHYHAKRGSLCAGCSKPITGRCITAMFKKFH 560

  Fly   546 PEHFVCAFCLKQLNKGTFKEQKDKPYCHTCFDKIFG 581
            |||||||||||||||||||||.||||||.||||:||
Mosquito   561 PEHFVCAFCLKQLNKGTFKEQNDKPYCHQCFDKLFG 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	48/51 (94%)
		LIM2_Paxillin_like	407..458	CDD:188723	47/50 (94%)
		LIM3_Paxillin_like	466..518	CDD:188724	49/51 (96%)
		LIM4_Paxillin	525..576	CDD:188795	48/50 (96%)
AgaP_AGAP008532	XP_316909.4	LIM1_Paxillin_like	363..415	CDD:259830	48/51 (94%)
		LIM2_Paxillin_like	422..473	CDD:188723	47/50 (94%)
		LIM3_Paxillin_like	481..533	CDD:188724	49/51 (96%)
		LIM4_Paxillin	540..591	CDD:188795	48/50 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	233	1.000	Domainoid score	I5338
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H136149
Inparanoid	1	1.050	748	1.000	Inparanoid score	I1635
OMA	1	1.010	-	-		QHG26243
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	1	1.000	-	-		oto108138
Panther	1	1.100	-	-	LDO	PTHR24216
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
TreeFam	1	0.960	-	-
	13	12.940