DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and AgaP_AGAP006540

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_316578.4	Gene:	AgaP_AGAP006540 / 1277139	VectorBaseID:	AGAP006540	Length:	334	Species:	Anopheles gambiae

Alignment Length:	155	Identity:	49/155 - (31%)
Similarity:	66/155 - (42%)	Gaps:	22/155 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 SMLGNLQANMSRQGVNTVQKGCCNACEKPIVGQVITALGK-TWHPEHFTCNHCSQELGTR-NFFE 388
            |:.|..||....:.        |.||.:||..|.:..:|. :||.....|..|...|..: :.|.
Mosquito     9 SLSGQCQAPKELRS--------CTACGEPISDQFLLDVGGCSWHSACLRCCICHTPLDHQPSCFL 65

  Fly   389 RDGFPYCEPDYHNLFSPRCAYCNGAI--LDKCVTALDKTWHTEHFFCAQCGQQF--GEEGFHERD 449
            |:...||:.||...|..:||.|:..|  .|....|.|..:|...|.|..||:|.  ||: |...|
Mosquito    66 RERQIYCKTDYTKRFGTKCARCSRTISATDWVRRARDLIFHLACFACDSCGRQLSTGEQ-FALVD 129

  Fly   450 GKPYCRNDYFEMFAPKC-----NGC 469
            .|..|:..|.|||  .|     :||
Mosquito   130 DKVLCKTHYSEMF--DCGTSSDDGC 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	17/53 (32%)
		LIM2_Paxillin_like	407..458	CDD:188723	19/54 (35%)
		LIM3_Paxillin_like	466..518	CDD:188724	3/9 (33%)
		LIM4_Paxillin	525..576	CDD:188795
AgaP_AGAP006540	XP_316578.4	LIM1_AWH	23..76	CDD:188759	16/52 (31%)
		LIM2_AWH	84..138	CDD:188765	19/54 (35%)
		Homeobox	167..219	CDD:278475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910