DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and AgaP_AGAP003429

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_003436478.1	Gene:	AgaP_AGAP003429 / 1272802	VectorBaseID:	AGAP003429	Length:	347	Species:	Anopheles gambiae

Alignment Length:	307	Identity:	83/307 - (27%)
Similarity:	129/307 - (42%)	Gaps:	76/307 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   348 CNACEKPIV--GQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYC 410
            |..|::...  .:::.:.|:.||.:.|.|..|.::.....|:|.:|..|||.|:|.||:|.||.|
Mosquito    19 CTRCDEGFEPHERIVNSNGQLWHTQCFVCAQCFRQFQDGIFYEFEGRKYCEKDFHILFAPCCAKC 83

  Fly   411 NGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGF---------HERDGKP-------------- 452
            |..::.:.:.|:...||.:.|.|.:|.....:.||         |:.:.|.
Mosquito    84 NNFVIGRVIKAMAANWHPQCFTCERCSIPLADSGFIRNQNRALCHDCNRKEKEVGLGKLVCNKCH 148

  Fly   453 -----------------------------------------YCRNDYFEMFA---------PKCN 467
                                                     |..||..|::.         |.|.
Mosquito   149 GIIDDAPLRFRGEVYHGYHFNCTSCGAELDSSAREVKNRSGYAANDMNELYCLRCHDRMGIPICG 213

  Fly   468 GCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGCSKPI 532
            .|.|.|.|..::||...||.:.|||..|.:||.|...::..|:.|||||||...|:||..|::.|
Mosquito   214 ACRRPIEERVVTALGKHWHVEHFVCAKCEKPFLGHRHYEKRGMAYCETHYHQLFGNLCFVCNQVI 278

  Fly   533 TGRCITAMFKKFHPEHFVCAFCLKQLN-KGTFKEQKDKPYCHTCFDK 578
            .|...||:.|.:...||.|:.|.::|: |..|.|..:||.|..|:::
Mosquito   279 AGDVFTALNKAWCVHHFSCSICDQKLDQKSKFFEYDEKPVCKKCYER 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	15/53 (28%)
		LIM2_Paxillin_like	407..458	CDD:188723	16/114 (14%)
		LIM3_Paxillin_like	466..518	CDD:188724	22/51 (43%)
		LIM4_Paxillin	525..576	CDD:188795	18/51 (35%)
AgaP_AGAP003429	XP_003436478.1	LIM1_PINCH	19..77	CDD:188717	17/57 (30%)
		LIM2_PINCH	80..131	CDD:188718	13/50 (26%)
		LIM3_PINCH	144..204	CDD:188719	4/59 (7%)
		LIM4_PINCH	210..263	CDD:188720	22/52 (42%)
		LIM5_PINCH	271..324	CDD:188721	19/52 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
TreeFam	0	0.000	Not matched by this tool.
	4	3.920