DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and AgaP_AGAP000731

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_311266.4	Gene:	AgaP_AGAP000731 / 1272320	VectorBaseID:	AGAP000731	Length:	420	Species:	Anopheles gambiae

Alignment Length:	319	Identity:	72/319 - (22%)
Similarity:	102/319 - (31%)	Gaps:	102/319 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 PDGPVGTVEEQIVQQKDSYTPNHAVPGQQVHQAYTSQATK-ELDDLMASLSDFKVSNGTNGIGN- 275
            |..||..  :.:::..:|..|        :|...|...|| ||....|.:.....:.|:..:|.
Mosquito    43 PSRPVAV--QDLLEFAESAGP--------IHSMMTMDVTKPELPSAAAGMGGGGGNTGSMSLGGL 97

  Fly   276 -GSHPQQHSSTVQHQTVTDYARPNKGSQQAHLTQTIEETTIVEDSREDQLDSMLGNLQANMSRQG 339
             .:.|||.....|.|           |||....|                       |:|.|..|
Mosquito    98 VPTGPQQQQQQQQQQ-----------SQQPQSQQ-----------------------QSNQSVVG 128

  Fly   340 VNTVQKGCCNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFS 404
            ...|..|              ...|...||:        |:|
Mosquito   129 GGPVGGG--------------GGGGGPPHPQ--------QQL----------------------- 148

  Fly   405 PRCAYCNGAILDK-CVTALDKTWHTEHFFCAQCGQQFGEEG--FHERDGKPYCRNDYFEMFAPK- 465
              ||.|...|.|: .:.|||..||.:...|..|..:.||.|  .:.:.....|:.||..:|...
Mosquito   149 --CAGCGKHIQDRFLLRALDLLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTG 211

  Fly   466 -CNGCNRAI--MENYISALNSQWHPDCFVCRDCRQPF-QGGSFFDHEGLPYCETHYHAK 520
             |..||:.|  .|..:.|.|:.:|.:||.|:.|...| .|..|:..|....||..|..:
Mosquito   212 FCAACNKVIPAFEMVMRARNNVYHLECFACQQCNHRFCVGDKFYLCENKILCEYDYEER 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	5/51 (10%)
		LIM2_Paxillin_like	407..458	CDD:188723	16/53 (30%)
		LIM3_Paxillin_like	466..518	CDD:188724	18/54 (33%)
		LIM4_Paxillin	525..576	CDD:188795
AgaP_AGAP000731	XP_311266.4	LIM1_LMO1_LMO3	149..203	CDD:188774	16/53 (30%)
AgaP_AGAP000731	XP_311266.4	LIM2_dLMO	213..267	CDD:188776	18/53 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910