Protein Alignment Pax and PRIC1_ANOGA

DIOPT Version :9

• Sequence 1: NP_001033913.1
• Gene: Pax / 35215
• FlyBaseID: FBgn0041789
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_308221.4
• Gene: PRIC1_ANOGA / 1269578
• VectorBaseID: AGAP007648
• Length: 923
• Species: Anopheles gambiae
• Alignment Length: 646
• Identity: 155/646 - (23%)
• Similarity: 221/646 - (34%)
• Gaps: 180/646 - (27%)

  Fly    42 QPQQPQPQYGTVQPKHQ-ALQQQQFVDNTP--------------------GYGSLRGKAQPQVY- 84
            |.|||| |.|  .|:|| .|||||..|::|                    |...||....|.:|
Mosquito    11 QTQQPQ-QNG--HPQHQLMLQQQQQADHSPHHHHHHHVHHATAHAYPYELGRSPLRSPQSPPLYS 72

  Fly    85 --------QEHYSVETRSPTAGH---DFNGSSTT-----PGYANQG---SLPRQAAGASTGLSEL 130
                    |.::|.: :.|||.|   ..:|:.|:     ||....|   ||.....|...|.:..
Mosquito    73 GKPPPPPPQSYHSYQ-QPPTAAHPPVSLSGAPTSMPGMMPGQQPPGMTLSLGGGGGGGGGGSAGD 136

  Fly   131 DSLLQDLQKIDVPVNYSTPVSKYNTMNSYATVEERPSVDSLLKELDNAHIYAVPN-GSAH---KS 191
            ..:|..||.       .:|.......|:.:|....||..|:..:   .|..:.|: ||:|   .|
Mosquito   137 CFMLPPLQP-------QSPDGLSTVTNTSSTATNAPSARSVYPQ---HHQPSYPSIGSSHHPFHS 191

  Fly   192 PTPGRHVTITVRETKTEKLTGPDGPVGTVEEQIVQ-QKDSYTPNHAV-----PGQQVHQAYTSQA 250
            |            .....|.||..|....::|..| |...|:..|.:     |...|..|
Mosquito   192 P------------ASAAALIGPSMPQHAQQQQQHQMQPHHYSSMHLLGPAGGPPSSVGPA----- 239

  Fly   251 TKELDDLMASLSDFKVSNGTNGIGNGS------------------HPQQHSSTVQHQTVTDY--A 295
              .:..:|.     ...:|..|:|.|:                  |....|.......:.:|  .
Mosquito   240 --SMVGMMG-----PGGHGGGGVGGGAGGIAGGVGGGPGGGMGGGHNYSQSDDDSGCALEEYTWV 297

  Fly   296 RPNKGSQQAHL-TQTIEE------TTIVEDSR-----------------------EDQLDSMLGN 330
            .|.....|.|| ...|.|      .:|.|..|                       |::.:..|.:
Mosquito   298 PPGLRPDQVHLYFSAIPEDKVPYVNSIGERHRVRQLLQQLPPHDNEVRYCHSLTDEERKELKLFS 362

  Fly   331 LQANMSRQGVNTVQK----GCCNAC-EKPIVGQVITALGK-----TWHPEHFTCNHCSQELGTRN 385
            .|......|..||::    ..|..| |....|.::....:     .|||..|.|..|.:.|....
Mosquito   363 AQRKREALGRGTVKQITTTLICERCGECASSGDMMVFASRFEPNTCWHPACFACCVCKELLVDLI 427

  Fly   386 FFERDGFPYCEPDYHNLFSPRCAYCNGAIL-DKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERD 449
            :|.|:...||...:.....|||:.|:..|| |:|..|..:.||.:||.|.:|.:|.|.:.:..||
Mosquito   428 YFHRENRLYCGRHHAETLKPRCSACDEIILADECTEAEGRAWHIKHFACFECDKQLGGQRYIMRD 492

  Fly   450 GKPYCRNDYFEMFAPKCNGCNR--AIMENYISALNSQWH--PDCFVCRDCRQPFQGGSFFDHEGL 510
            |||||.:.:..|||..|:.|:.  .:.:..:|.....||  ..||.|..||....|..|....|.
Mosquito   493 GKPYCLHCFDAMFAEYCDYCSEPIGVDQGQMSHDGQHWHATDQCFACSTCRCSLLGRPFLPRRGE 557

  Fly   511 PYCE---------------THYHAKRGSLCAGCSKPI------TGRCITAMFKKFHPEHFV 550
            .||.               .|..::.....|...:|:      |||     ....|.||.|
Mosquito   558 IYCSIACSKGEPPTPSDEYAHRSSQPSHTAARSPEPLRSPERGTGR-----LSPPHTEHEV 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	15/57 (26%)
		LIM2_Paxillin_like	407..458	CDD:188723	22/51 (43%)
		LIM3_Paxillin_like	466..518	CDD:188724	16/70 (23%)
		LIM4_Paxillin	525..576	CDD:188795	9/32 (28%)
PRIC1_ANOGA	XP_308221.4	PET_Prickle	283..378	CDD:193602	17/94 (18%)
		LIM1_Prickle	384..442	CDD:188799	15/57 (26%)
		LIM2_Prickle	447..502	CDD:188802	24/54 (44%)
		LIM3_Prickle	507..565	CDD:188804	15/57 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
TreeFam	0	0.000	Not matched by this tool.
	2	1.910