DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and Lmx1a

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_387501.1	Gene:	Lmx1a / 110648	MGIID:	1888519	Length:	382	Species:	Mus musculus

Alignment Length:	124	Identity:	45/124 - (36%)
Similarity:	59/124 - (47%)	Gaps:	7/124 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   404 SPR--CAYCNGAILDKCVTAL-DKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPK 465
            ||:  |..|...|.|:.:..| |..||.:...||.|.:......|: ||.|.||:..|.::||.|
Mouse    30 SPKSVCEGCQRVISDRFLLRLNDSFWHEQCVQCASCKEPLETTCFY-RDKKLYCKYHYEKLFAVK 93

  Fly   466 CNGCNRAIMEN--YISALNSQWHPDCFVCRDC-RQPFQGGSFFDHEGLPYCETHYHAKR 521
            |.||..||..|  .:.|..|.:|..||.|..| ||..:|..|...||...|:..|..:|
Mouse    94 CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKER 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830
		LIM2_Paxillin_like	407..458	CDD:188723	17/51 (33%)
		LIM3_Paxillin_like	466..518	CDD:188724	20/54 (37%)
		LIM4_Paxillin	525..576	CDD:188795
Lmx1a	NP_387501.1	LIM1_Lmx1a	35..86	CDD:188756	17/51 (33%)
		LIM2_Lmx1a_Lmx1b	94..148	CDD:188764	20/53 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..208
		Homeobox	198..252	CDD:365835
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	252..286
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910