DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and lmx1b.2

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_031755234.1	Gene:	lmx1b.2 / 100497942	XenbaseID:	XB-GENE-920041	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	142	Identity:	42/142 - (29%)
Similarity:	71/142 - (50%)	Gaps:	7/142 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   389 RDGFPYCEPDYHNLFSPRCAYCNGAILDKCVTAL-DKTWHTEHFFCAQCGQQFGEEGFHERDGKP 452
            |:..|:...|:.  .:..||.|...|.|:.:..: |::||.....||.|.|......:: |:.:.
Frog    11 REHSPFLGLDHK--INEVCAGCGNTISDRFLLRVNDRSWHECCVKCAACLQILSGTCYY-RNRQL 72

  Fly   453 YCRNDYFEMFAPKCNGCNRAIM--ENYISALNSQWHPDCFVCRDC-RQPFQGGSFFDHEGLPYCE 514
            ||:.||.::||.|||.|.:.::  |..:..|::.:|..||.|.:| |:..:|..|...||...|.
Frog    73 YCKEDYDKLFATKCNSCLKTVLPSELIMRVLSNVYHVACFFCCECERRLERGDEFVLKEGQLLCR 137

  Fly   515 THYHAKRGSLCA 526
            :.|..::..|.|
Frog   138 SDYEREKEMLSA 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	3/10 (30%)
		LIM2_Paxillin_like	407..458	CDD:188723	15/51 (29%)
		LIM3_Paxillin_like	466..518	CDD:188724	16/54 (30%)
		LIM4_Paxillin	525..576	CDD:188795	1/2 (50%)
lmx1b.2	XP_031755234.1	LIM1_Lmx1b	27..79	CDD:188757	16/52 (31%)
		LIM	86..140	CDD:413332	16/53 (30%)
		Homeobox	184..238	CDD:395001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910