DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and prickle3

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_031747016.1	Gene:	prickle3 / 100490600	XenbaseID:	XB-GENE-940034	Length:	571	Species:	Xenopus tropicalis

Alignment Length:	320	Identity:	82/320 - (25%)
Similarity:	124/320 - (38%)	Gaps:	51/320 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 QKDSYTPNHAVPGQQVHQAYTSQATKELDDLMASLSDFKVSNGTNGIGNGSHPQQHSST------ 285
            :|.::.|:...| .||||.:.....|::..:.:....:::....:.:     |...|.|
Frog    88 EKYAWAPSGLNP-MQVHQFFKCFPEKKIPYISSPGERYRLKQLLHQL-----PPHDSETWCCCLF 146

  Fly   286 -------VQHQTVTDYAR---PNKGSQQAHLTQTIEETTIVEDSREDQLDSMLGNLQANMSRQGV 340
                   |..:.|...||   ..:|.:        ||..:|..|::.:|:    ||.....|...
Frog   147 CARPSTAVSCKLVLSQARYCCSLQGEE--------EEELLVLFSQKRRLE----NLGRGCVRPVS 199

  Fly   341 NTVQKGCCNACEKPI-VGQVI-----TALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDY 399
            .|:....|..|...| ||.|.     ..||..|||:.|||..|.:.|....:|.:||..||...:
Frog   200 GTMSGTVCQQCGHQISVGDVAVFASRAGLGFCWHPQCFTCAQCLELLCDLIYFYQDGKVYCGRHH 264

  Fly   400 HNLFSPRCAYCNGAILD-KCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFA 463
            ..|..|||..|:..|.. :|..|....|||.||.|.:|....|...:..:|.:|:|.:.|..::|
Frog   265 AELKRPRCLACDEVIFSLECTQAEGFHWHTRHFCCFECECPLGGHRYIMKDQRPFCCSCYDRLYA 329

  Fly   464 PKCNGCNR--------AIMENYISALNSQWH--PDCFVCRDCRQPFQGGSFFDHEGLPYC 513
            ..|:.|..        .|.|..::.....||  ..||.|..|.....|..|...:|..||
Frog   330 QYCDSCGECIDGLFLLGIDEGQLTYGGQHWHASESCFCCGRCGVCLLGRPFLPRQGQIYC 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	21/57 (37%)
		LIM2_Paxillin_like	407..458	CDD:188723	16/51 (31%)
		LIM3_Paxillin_like	466..518	CDD:188724	15/58 (26%)
		LIM4_Paxillin	525..576	CDD:188795
prickle3	XP_031747016.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000