DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and arx

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_002933659.1	Gene:	arx / 100486727	XenbaseID:	XB-GENE-483940	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	349	Identity:	72/349 - (20%)
Similarity:	120/349 - (34%)	Gaps:	66/349 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 HYSVET--------RSPTAGHDF----------------NGSSTTPGYANQGSLPRQAAGASTGL 127
            ||..||        :|||....:                .|:.:.|..|::....:...|:..|.
Frog     4 HYPEETSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAQSLPSLAHRLDPDKTLEGSPKGN 68

  Fly   128 SELDS---LLQDLQKIDVPVNYSTPVSKYNTMNSYATVEERPSVDSLLKELDNAHIYAVPNGSAH 189
            :..::   |...|:::..||..|..:......::.:.|......|.:|. |..|......|.|..
Frog    69 AAFEADLHLPPKLRRLYGPVGGSGRIHLQAVADARSGVPRSEKTDRILL-LGGAGENTWDNHSLK 132

  Fly   190 KSPTPGRHVTI----TVRETKTEKLTGPDGPVGTVEEQIVQQKDSYTPNHAVPGQQVHQAYTSQA 250
            .|..|  .|:|    :.||.....|.....|.|.:::.  ||:...:...|....|......||:
Frog   133 ISQAP--QVSISRSKSYRENSAPLLREEHSPEGLLQQS--QQQIQTSATTACTSLQDRLGALSQS 193

  Fly   251 TKELDDLMASLSDFKVSNGTNGIGNGSHPQQHSSTVQHQTVTDYARPNKGSQQAHLTQTIEET-T 314
            .::.||......|.:.........|..|...:||......:.:...|...|||:...|..... |
Frog   194 PRDEDDDDEEDEDEEEEEEEEDEANKQHNPNNSSNPNRAHLQEQQHPQFQSQQSQQQQPPPGCGT 258

  Fly   315 IVEDSREDQLDSMLGNLQANMSRQGVNTVQKGCCNACEKPIVG-------------------QVI 360
            ..|.|.:::|  ||.:..|: .:.|.::|   |.:|......|                   ::.
Frog   259 DAELSPKEEL--MLHSSDAD-GKDGEDSV---CLSAGSDSEEGMLKRKQRRYRTTFTSYQLEELE 317

  Fly   361 TALGKTWHPEHFTCNHCSQELGTR 384
            .|..||.:|:.||    .:||..|
Frog   318 RAFQKTHYPDVFT----REELAMR 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	11/56 (20%)
		LIM2_Paxillin_like	407..458	CDD:188723
		LIM3_Paxillin_like	466..518	CDD:188724
		LIM4_Paxillin	525..576	CDD:188795
arx	XP_002933659.1	Homeobox	305..358	CDD:365835	9/37 (24%)
arx	XP_002933659.1	OAR	500..518	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910