DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and mical3

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_031754432.1	Gene:	mical3 / 100486205	XenbaseID:	XB-GENE-996271	Length:	2242	Species:	Xenopus tropicalis

Alignment Length:	348	Identity:	78/348 - (22%)
Similarity:	125/348 - (35%)	Gaps:	73/348 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 TRSPTA-----GHDFNGSSTTPGYANQGSLPRQAAG--ASTGLSELDSLLQDLQKIDVPVNYSTP 149
            |:||.:     |...:...|......:.|   .|:|  ..|..|| |......|:.:.|.:.|..
Frog   644 TKSPISFLSKLGQTISRKRTPKDKKEKDS---DASGKRRKTSQSE-DEEAPRTQREEKPASVSAV 704

  Fly   150 VSKYNTMNSYATVEERPSVDS--LLKELDNAHIYAVPNGSAHKS-PT-PGRHVTITVRETKTEKL 210
            ..:.|...|.|...:..|:.:  |.|..:||   ..||....|. || |.:.   .::...:::.
Frog   705 AERRNETASAAGQNKVKSMATQLLAKFEENA---PAPNAGLRKQRPTLPYQE---RLQNQASQRQ 763

  Fly   211 TGPDGPVGTVEEQIVQQKDSYTPNHAVPGQQVHQAYTSQATKELDDLMASLS--DFKVSNGTNGI 273
            |.|         |..|::|:..|.              ...|::..|.|..|  ...|...|..:
Frog   764 TEP---------QWKQRRDNQRPR--------------SCPKKVITLNAGSSPVPLPVLQTTPVL 805

  Fly   274 GNG----------SHPQQHSSTVQ-HQTVTDYA--RPNKGSQQAHLTQTIEETTIVEDSREDQLD 325
            |:.          |..|..|...| .||:...:  ||:..|..|...:.|:..|....|..:|:.
Frog   806 GSSRWEQCPTLERSETQSRSPAGQWQQTLAQRSSDRPSSPSSDALRQKYIKMYTGGVSSLAEQIA 870

  Fly   326 SMLGNLQANMSRQG--VNTVQK---------GCCNACEKPI-VGQVITALGKTWHPEHFTCNHCS 378
            :.|...:......|  |.:.:|         ..|..|.:.: |.:.::|.||.:|...|.|::||
Frog   871 NQLQKKETPKPLFGKKVGSFRKEFPQNLGGSDVCYFCRRRVYVMERLSAEGKFFHRSCFKCDYCS 935

  Fly   379 Q--ELGTRNFFERDGFPYCEPDY 399
            .  .|....:...||..||:|.|
Frog   936 TTLRLSCYAYDLEDGKFYCKPHY 958

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	18/55 (33%)
		LIM2_Paxillin_like	407..458	CDD:188723
		LIM3_Paxillin_like	466..518	CDD:188724
		LIM4_Paxillin	525..576	CDD:188795
mical3	XP_031754432.1	UbiH	87..>226	CDD:357568
		CH_MICAL3	514..624	CDD:409100
		LIM_Mical	904..958	CDD:188823	17/53 (32%)
		PHA03247	1222..>1479	CDD:223021
		Herpes_BLLF1	<1358..1622	CDD:282904
		DUF3585	2055..2220	CDD:403377
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910