DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pax and LIMS4

DIOPT Version :9

Sequence 1:NP_001033913.1 Gene:Pax / 35215 FlyBaseID:FBgn0041789 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_001358269.1 Gene:LIMS4 / 100288695 HGNCID:39941 Length:398 Species:Homo sapiens


Alignment Length:359 Identity:105/359 - (29%)
Similarity:160/359 - (44%) Gaps:48/359 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   259 ASLSDFKVSNGTNGIGNGSHPQ-QHSSTVQHQTVTD-YARPNKGSQQAHLTQTIEE--------T 313
            |:|:....:|||......|..| :||....::...| ||:.|..:..|  :.|.|.        .
Human    21 AALNTVHEANGTEDERAVSKLQRRHSDVKVYKEFCDFYAKFNMANALA--SATCERCKGGFAPAE 83

  Fly   314 TIVEDSREDQLDSMLGNLQANMSRQGVNTVQKG---------------------CCNACEKPIVG 357
            |||..:.|      |.:.|..:..|......:|                     ||:.|.:.|:|
Human    84 TIVNSNGE------LYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIG 142

  Fly   358 QVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPR------CAYCNGAILD 416
            :||.|:..:||||.|.|:.|.:.|....|.:..|...|.| .||....|      |..|:..|.:
Human   143 RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP-CHNREKARGLGKYICQKCHAIIDE 206

  Fly   417 KCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNRAIMENYISAL 481
            :.:...:..:|.:||.||.||:....:. .|..|:.||...:.:|..|.|..|.|.|....::|:
Human   207 QPLIFKNDPYHPDHFNCANCGKDLTADA-QELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAM 270

  Fly   482 NSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGCSKPITGRCITAMFKKFHP 546
            ..|||.:.|||..|.:||.|...::.:||.||||||:...|.:|..|::.|.|..::|:.|.:..
Human   271 GKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCV 335

  Fly   547 EHFVCAFCLKQLN-KGTFKEQKDKPYCHTCFDKI 579
            ..|.|:.|..:|. |..|.|...||.|..|::|:
Human   336 NCFACSTCNTKLTLKDKFVEIDLKPVCKHCYEKM 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PaxNP_001033913.1 LIM1_Paxillin_like 348..400 CDD:259830 19/51 (37%)
LIM2_Paxillin_like 407..458 CDD:188723 14/50 (28%)
LIM3_Paxillin_like 466..518 CDD:188724 22/51 (43%)
LIM4_Paxillin 525..576 CDD:188795 16/51 (31%)
LIMS4NP_001358269.1 LIM1_PINCH 72..130 CDD:188717 9/63 (14%)
LIM2_PINCH 133..184 CDD:188718 19/51 (37%)
LIM3_PINCH 197..247 CDD:188719 14/50 (28%)
LIM4_PINCH 253..306 CDD:188720 22/52 (42%)
LIM5_PINCH 314..367 CDD:188721 17/52 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1593918at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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