DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and fhl5

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001116957.1	Gene:	fhl5 / 100144736	XenbaseID:	XB-GENE-1002465	Length:	282	Species:	Xenopus tropicalis

Alignment Length:	243	Identity:	70/243 - (28%)
Similarity:	106/243 - (43%)	Gaps:	8/243 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 NTVQKGCCNACEKPIV--GQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLF 403
            |::....|..|:|||.  .:.:......||...|.|:.|...|..:.|..:|....|...|...:
Frog    34 NSLFANLCERCKKPIECNSKDLAYKDSHWHETCFKCDKCDHSLVEKPFAAKDELLLCIECYSTEY 98

  Fly   404 SPRCAYCNGAIL--DKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKC 466
            |.:|..|...|:  .:.:......||...|.|..|.:..|.:.|..::.|.||...|.:.||.:|
Frog    99 SSKCFGCRATIMPGSRKMEYNGSNWHETCFVCQSCREPVGNKPFIPKESKIYCMPCYEKQFANQC 163

  Fly   467 NGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGCSKP 531
            ..|.:||.:..:|....|||.:||||..|::...|......:..|||...:.......||.|:||
Frog   164 KSCRKAITKGGLSFQEQQWHRECFVCTSCKKNLVGEKSTSRDESPYCVDCFDNLYAKKCAACAKP 228

  Fly   532 ITG----RCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKDKPYCHTC 575
            |||    :.|:...:::|.:.|.||.|.|.|....|...:|...|.:|
Frog   229 ITGQGGAKYISFEDRQWHSDCFTCAKCSKSLVGEKFHTNEDDVLCPSC 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	14/53 (26%)
		LIM2_Paxillin_like	407..458	CDD:188723	13/52 (25%)
		LIM3_Paxillin_like	466..518	CDD:188724	17/51 (33%)
		LIM4_Paxillin	525..576	CDD:188795	20/55 (36%)
fhl5	NP_001116957.1	LIM	<6..33	CDD:351770
		LIM1_FHL	37..95	CDD:188729	14/57 (25%)
		LIM2_FHL	102..155	CDD:188731	13/52 (25%)
		LIM3_FHL	163..214	CDD:188732	17/50 (34%)
		LIM4_FHL	222..277	CDD:188733	20/55 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910