DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and prickle2

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_031757102.1	Gene:	prickle2 / 100126208	XenbaseID:	XB-GENE-482891	Length:	893	Species:	Xenopus tropicalis

Alignment Length:	294	Identity:	80/294 - (27%)
Similarity:	124/294 - (42%)	Gaps:	47/294 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 PG---QQVHQAYTSQATKELDDLMASLSDFKVSNGTNGIGNGSHPQQHSSTVQHQTVTDYARPNK 299
            ||   :||||.|            :.|.|.||.. .|..|..|..:|    :.||     ..|:
Frog    98 PGLKPEQVHQYY------------SCLPDDKVPY-VNSPGEKSRIKQ----LLHQ-----LPPH- 139

  Fly   300 GSQQAHLTQTIEETTIVEDSREDQLDSMLGNLQANMSRQGVN----TVQKGCCNACEKPIVGQVI 360
             ..:.....:::|    |:.||.:|.|. ...:.|:.|..|.    |:....|..|...|.|..:
Frog   140 -DNEVRYCNSLDE----EEKRELKLFSN-QRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDM 198

  Fly   361 TAL------GKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYCNGAIL-DKC 418
            ...      |..|||:.|.|..|::.|....:|.:||..||...:.....||||.|:..|. |:|
Frog   199 AVFASRAGHGVCWHPQCFVCIICNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADEC 263

  Fly   419 VTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNR--AIMENYISAL 481
            ..|..:.||.:||.|.:|....|.:.:..::|:|||.|.:..::|..|:.|.:  .|.:..::..
Frog   264 TEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCNCFESLYAEYCDTCAQHIGIDQGQMTYD 328

  Fly   482 NSQWH--PDCFVCRDCRQPFQGGSFFDHEGLPYC 513
            ...||  .:||.|..|::...|..|...:|..:|
Frog   329 GQHWHATENCFCCAHCKKSLLGRPFLPKQGQIFC 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	17/57 (30%)
		LIM2_Paxillin_like	407..458	CDD:188723	19/51 (37%)
		LIM3_Paxillin_like	466..518	CDD:188724	13/52 (25%)
		LIM4_Paxillin	525..576	CDD:188795
prickle2	XP_031757102.1	PET_Prickle	82..178	CDD:193602	27/108 (25%)
		LIM1_Prickle	186..244	CDD:188799	17/57 (30%)
		LIM2_Prickle	249..304	CDD:188802	21/54 (39%)
		LIM3_Prickle	309..367	CDD:188804	13/54 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000