Protein Alignment Pax and tgfb1i1

DIOPT Version :9

• Sequence 1: NP_001033913.1
• Gene: Pax / 35215
• FlyBaseID: FBgn0041789
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_012825390.2
• Gene: tgfb1i1 / 100038241
• XenbaseID: XB-GENE-493249
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 612
• Identity: 230/612 - (37%)
• Similarity: 287/612 - (46%)
• Gaps: 174/612 - (28%)

  Fly    30 ALLADLQNSVP--------GQPQQPQPQYGTVQPKHQALQQQQFVDNTPGYGSLRGKAQPQVYQE 86
            |||||||.:.|        ..|::|||
 Frog     6 ALLADLQITTPPRCPVLLTDSPEKPQP-------------------------------------- 32

  Fly    87 HYSVETRSPTAGHDFNGSSTTPGYANQGSLPRQAAGASTGLSELDSLLQDLQKIDVPVNYSTPVS 151
               .|||.|...:|                ||.|....|...|                 :.||.
 Frog    33 ---TETRPPPPPYD----------------PRTAMSNKTSDHE-----------------TIPVD 61

  Fly   152 K---YNTMNSYATVEERPS-------VDSLLKELDNAHIYAVPNGSAHKSPTPGRHVTITVRETK 206
            |   |:|:..|......|:       :|.||.|| ||..:.:.:....:.||..|:
 Frog    62 KDHLYSTVQKYPLPSVSPALGGGLCELDRLLNEL-NATQFNITDEIMSQFPTRDRN--------- 116

  Fly   207 TEKLTGPDGPVGTVEEQIVQQKDSYTPNHAVPGQQVHQAYTSQATKELDDLMASLSDFKVSNGTN 271
                          |::...||::          :......|.||.|||.||||||||...|..:
 Frog   117 --------------EQKAEAQKEA----------EKRALSASSATLELDRLMASLSDFHKQNTVS 157

  Fly   272 ------GIGNGSHPQQHSSTVQHQTVTDYARPN-------KGSQQA-------------HL---T 307
                  |...||.........:     |.:.|.       |.|:.|             ||   |
 Frog   158 QEVEAPGTFKGSEAVSRPGDTE-----DLSSPRSIEDGVPKASEDAPSPKSFEVVSAPVHLDVKT 217

  Fly   308 QTIEETTIVEDS-------------REDQLDSMLGNLQANMSRQGVNTVQKGCCNACEKPIVGQV 359
            ..:...:.|.||             |.| |||||..||:.:..||:.|..||.|.:|::||.|||
 Frog   218 DQVISASRVPDSVSGCKVPEATSGPRSD-LDSMLVKLQSGLKLQGIETQSKGLCESCQRPIAGQV 281

  Fly   360 ITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYCNGAILDKCVTALDK 424
            :||||.|||||||.|.||...:||.||||:||.||||.||..|::||||.|...|:...||||..
 Frog   282 VTALGHTWHPEHFVCAHCHALIGTTNFFEKDGRPYCEKDYFMLYAPRCALCELPIVQNMVTALGC 346

  Fly   425 TWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNRAIMENYISALNSQWHPDC 489
            |||.|||.|..|.:..|||||||:||:.||.:|||.:|...|.||:.|:.|:|||||...|||.|
 Frog   347 TWHPEHFCCKVCKKPIGEEGFHEKDGEQYCSDDYFRLFGAVCAGCSEAVKESYISALGGLWHPQC 411

  Fly   490 FVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGCSKPITGRCITAMFKKFHPEHFVCAFC 554
            |||..|..||..||||:|||||.||||||::||||||||.:||||||:|||.|||||:|..|.||
 Frog   412 FVCHVCHTPFINGSFFEHEGLPLCETHYHSRRGSLCAGCEQPITGRCVTAMGKKFHPQHLNCTFC 476

  Fly   555 LKQLNKGTFKEQKDKPYCHTCFDKIFG 581
            |:|||||||:|...||||..|:.:::|
 Frog   477 LRQLNKGTFREHDGKPYCQACYARLYG 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	34/51 (67%)
		LIM2_Paxillin_like	407..458	CDD:188723	27/50 (54%)
		LIM3_Paxillin_like	466..518	CDD:188724	33/51 (65%)
		LIM4_Paxillin	525..576	CDD:188795	35/50 (70%)
tgfb1i1	XP_012825390.2	Paxillin	<61..>117	CDD:397550	15/79 (19%)
		LIM1_Paxillin_like	270..322	CDD:259830	34/51 (67%)
		LIM2_Paxillin_like	329..380	CDD:188723	27/50 (54%)
		LIM3_Paxillin_like	388..440	CDD:188724	33/51 (65%)
		LIM4_Paxillin_like	447..498	CDD:188725	35/50 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1093
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040