Protein Alignment CG17544 and ACOX2

DIOPT Version :10

• Sequence 1: NP_609961.2
• Gene: CG17544 / 35213
• FlyBaseID: FBgn0032775
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: XP_047304998.1
• Gene: ACOX2 / 8309
• HGNCID: 120
• Length: 747
• Species: Homo sapiens
• Alignment Length: 698
• Identity: 195/698 - (27%)
• Similarity: 319/698 - (45%)
• Gaps: 57/698 - (8%)

  Fly    10 PDLPSGGPLAVYRKRANFDWKRLRLIFE-KEQGLRIKYKVWRRLENDPLFAHPSRTLPMDEQKRL 73
            ||:.|      .|...:||.:||..|.: ..|...::.||...:.:.|.|:..........::..
Human    86 PDIES------ERYMQSFDVERLTNILDGGAQNTALRRKVESIIHSYPEFSCKDNYFMTQNERYK 144

  Fly    74 CAMQVNRMKHLDLVPKEIESLSFSAKTKYLMYINEALACYSPSLSVKIALGV-GLFNNAIRAMGT 137
            .||:  |..|:.|:.:.:..|....:..|         .|. :||..:||.: .:|..|:|::|:
Human   145 AAMR--RAFHIRLIARRLGWLEDGRELGY---------AYR-ALSGDVALNIHRVFVRALRSLGS 197

  Fly   138 EKH-QKYIEAAWNREVITCLAITELSHGSNTKSIRTTATYDPTTQEFVINTPDFEAAKCWVGNLG 201
            |:. .|:.....|.::|...|.|||.||:..:.:.|.||||..||||||::|...|.|.|.|:||
Human   198 EEQIAKWDPLCKNIQIIATYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTLTATKWWPGDLG 262

  Fly   202 KTATVAMTFANLYTADGQNHGLHGFLIPIRDPKTLLSYPGVLVGDIGEKCGLNGIDNGFVVFTNY 266
            ::||.|:..|.| ...|...|:|.|::|||..:.....||:::||||.|...:..||||:...:.
Human   263 RSATHALVQAQL-ICSGARRGMHAFIVPIRSLQDHTPLPGIIIGDIGPKMDFDQTDNGFLQLNHV 326

  Fly   267 RIPRDNLLNRTSDVTPEGVYESVFTEPGKVLG---AALESFSAGRIGIMQESANTLCSAAVIAVR 328
            |:||:|:|:|.:.|.|:|.|..:.|.....|.   ..:|..|...:.|:|:       |.|||:|
Human   327 RVPRENMLSRFAQVLPDGTYVKLGTAQSNYLPMVVVRVELLSGEILPILQK-------ACVIAMR 384

  Fly   329 YSAVRKQFGPERHGEEMAILEYQLHQYRIFPYLAAACVQKIATEELTSTYMEIIARSQADSNGFD 393
            ||.:|:|........|..:|:||..|.::||.||.:    .|...|..:.:|....|..     .
Human   385 YSVIRRQSRLRPSDPEAKVLDYQTQQQKLFPQLAIS----YAFHFLAVSLLEFFQHSYT-----A 440

  Fly   394 VLTQNAA---EIHALISSSKPLITWAARDAIQEAREACGGHGYLQAAKLGQMRTDHDPLCTYEGD 455
            :|.|:.:   |:|||.:..|.:::.......:..|.|||||||.:.:.|..:.|.....|||||:
Human   441 ILNQDFSFLPELHALSTGMKAMMSEFCTQGAEMCRRACGGHGYSKLSGLPSLVTKLSASCTYEGE 505

  Fly   456 NNVLGQQASNWLLRQWSAKELETPI--GSVKFLERRSELLALNYASLAQKTPIASWQF---SLRC 515
            |.||..|.:.:|::.:    |:|.:  ||.........:..|....||:.....:..|   .|..
Human   506 NTVLYLQVARFLVKSY----LQTQMSPGSTPQRSLSPSVAYLTAPDLARCPAQRAADFLCPELYT 566

  Fly   516 YEW--LLCHLMAKTTAHIEGQLAAGSSKFEARNNSQVAGARELSLAYAEYYALTRYVDHVSTLTV 578
            ..|  :...|:..:..|::....:|:.:.||.|.:.|... :.:..:..|..:..:.:.:..|..
Human   567 TAWAHVAVRLIKDSVQHLQTLTQSGADQHEAWNQTTVIHL-QAAKVHCYYVTVKGFTEALEKLEN 630

  Fly   579 EAPYASVLRLLFDVYAMWLLEKHMTTFYVGGFAAGRDFSAAVRQLLLDSCLKLKDVAVSVADAIS 643
            |.....||:.|.|::|:..:..:...|....|.:|.....| |...||....::..|:.:.||..
Human   631 EPAIQQVLKRLCDLHAIHGILTNSGDFLHDAFLSGAQVDMA-RTAYLDLLRLIRKDAILLTDAFD 694

  Fly   644 PPDFALNSVIARADGLLYENLQNEFMTNEGAFQRPSWWRDVIIPQAQS 691
            ..|..|||.:...||.:||.|......:....|....:.:.|.|..||
Human   695 FTDQCLNSALGCYDGNVYERLFQWAQKSPTNTQENPAYEEYIRPLLQS 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17544	NP_609961.2	AXO	16..670	CDD:173839	187/669 (28%)
ACOX2	XP_047304998.1	ACAD	86..721	CDD:447864	190/675 (28%)