DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG17544 and Egm

DIOPT Version :9

Sequence 1:NP_001163015.1 Gene:CG17544 / 35213 FlyBaseID:FBgn0032775 Length:693 Species:Drosophila melanogaster
Sequence 2:NP_610687.1 Gene:Egm / 36242 FlyBaseID:FBgn0086712 Length:639 Species:Drosophila melanogaster


Alignment Length:576 Identity:112/576 - (19%)
Similarity:188/576 - (32%) Gaps:213/576 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 LFAHPSRTLPMDEQKRLCAMQVNRMKHLDLVPKEIESLS-----------FSAKTKY----LMYI 106
            |.|:| ..:|.||..:| ...:..:|:..:.|:|.|..|           .:..|.|    ..:.
  Fly    82 LLAYP-EVIPRDEMAQL-ENSLLPLKNYFVEPRETEETSPETLRQLGLYGLNVSTDYEGKGYGWS 144

  Fly   107 NEALACYSPSLSVKIALGVGLFN---NAIRAMGTE-KHQKYIEAAWNREVITCLAITELSHGSNT 167
            ...:|....|..:.:.||:....   :.::.:||. :.|:|::.....::|...||.|:| ....
  Fly   145 ASLMASEPDSTDINVTLGLQTHRVVVDLLKEVGTPLQQQRYLQDLATGKLIGTEAIYEIS-PPEE 208

  Fly   168 KSIRTTATYDPT--------TQEFVINTPDFEAAKCWV----------GNLGKTATVAMTFANLY 214
            ....|||...|.        .:.|||.||. |.....|          |.||:..|:       :
  Fly   209 DYFNTTAELFPEYGKWQLNGEKSFVICTPG-ERQLFLVLAQTQQPNVPGVLGRGTTI-------F 265

  Fly   215 TADGQNHG---------------------------------------------------LHGFLI 228
            ..|.|..|                                                   |.|.|:
  Fly   266 LVDSQQEGVRLGEKHATFGCRKAEIRRVHFEGVKLGEDQVVGLPHDGNRYSEQLVRSSRLRGSLV 330

  Fly   229 PIRDPKTLLSYPGVLVGDIGE------KCGLNGIDNGFVVFTNYRIPR---------------DN 272
            .:...|.||:       ::.:      :||:...|   :..|...:.|               ..
  Fly   331 GLSLAKKLLN-------ELAQYTVNTTQCGVQLQD---LELTRIHMSRAMCSVYAMESMLYLTAG 385

  Fly   273 LLN--RTSDVTPEGVYESVFT----------EPGKVLGAALESFSAGRIGIMQ--------ESAN 317
            ||:  |..|||.|......||          ..|.|...:|.|.....:|:..        ||.:
  Fly   386 LLDEFRAQDVTLESAITKYFTLRQVYAIASQNLGVVGPKSLLSGETTELGLRDAAQLCTQGESLD 450

  Fly   318 TL-CSAAVIAVRY------SAVRKQFGP------------ERHGEEMAILEYQLHQYRIFPYL-- 361
            || ...|:..:::      :.|||...|            :.:..:....:.||.:: :.|.|  
  Fly   451 TLGMFIALTGLQHAGQAMNTGVRKSRNPLFNPGHIFGKFLDNNSIDNPKTKMQLSEH-VHPSLEA 514

  Fly   362 AAACVQ------KIATEELTSTYMEIIARSQADSNGFDVLTQNAAEIHALISSSKPLITWAARDA 420
            ||.|::      ::|.|.:.:.:...:...|::       .|..||:..||.:     .||:  .
  Fly   515 AAQCIELSVARLQMAVELMFTKHGNAVVERQSE-------MQRLAEVGTLIYA-----MWAS--V 565

  Fly   421 IQEAREACGG-----HGYLQAAKL-----GQMRTDHDPLCT--YEG-----DNNVL 459
            .:.:|..|.|     |..|.|..:     .::||    |||  |.|     |||::
  Fly   566 ARASRSYCIGLPLADHELLTATAICSEGRDRVRT----LCTEIYGGHFVNNDNNLV 617

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17544NP_001163015.1 AXO 16..670 CDD:173839 112/576 (19%)
PLN02443 18..687 CDD:178062 112/576 (19%)
EgmNP_610687.1 ACAD 92..457 CDD:173838 70/384 (18%)
CaiA 122..439 CDD:224871 58/335 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1960
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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