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Protein Alignment CG17544 and GCDH

DIOPT Version :9

Sequence 1:	NP_001163015.1	Gene:	CG17544 / 35213	FlyBaseID:	FBgn0032775	Length:	693	Species:	Drosophila melanogaster
Sequence 2:	NP_000150.1	Gene:	GCDH / 2639	HGNCID:	4189	Length:	438	Species:	Homo sapiens

Alignment Length:	471	Identity:	89/471 - (18%)
Similarity:	171/471 - (36%)	Gaps:	132/471 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RANFDWKRLRLIFEKEQGLRIKYKVWRRLENDPLFAHPS-------RTLPMDEQKRLCAMQVNRM 81
            |..|||:. .|:.|::            |..|.:....:       |.:|     |:.....|.:
Human    45 RPEFDWQD-PLVLEEQ------------LTTDEILIRDTFRTYCQERLMP-----RILLANRNEV 91

  Fly    82 KHLDLVPK-----------------EIESLSFSAKTKYLMYINEALACYSPSLSVKIALGVGLFN 129
            .|.:::.:                 .:.|:::....:.|..::..   |..::||:.:|.:
Human    92 FHREIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSG---YRSAMSVQSSLVM---- 149

  Fly   130 NAIRAMGT-EKHQKYIEAAWNREVITCLAITELSHGSNTKSIRTTATYDPTTQEFVINTPDFEAA 193
            :.|.|.|: |:.|||:......|::.|..:||.:.||:..|:.|.|.|:.:.:.:.:|     ..
Human   150 HPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLN-----GT 209

  Fly   194 KCWVGNLGKTATVAMTFANLYT--ADGQNHGLHGFLIPIRDPKTLLSYPGVLVGDIGEKCGLNGI 256
            |.|:.|        ...|:|:.  |..::..:.|||:.       ....|:....|..|..|...
Human   210 KTWITN--------SPMADLFVVWARCEDGCIRGFLLE-------KGMRGLSAPRIQGKFSLRAS 259

  Fly   257 DNGFVVFTNYRIPRDNLLNRTSDVTPEGVYESVFTEPG-KVLGAALESFSAGRIGIMQE--SANT 318
            ..|.::.....:|.:|:|                  || ..||......:..|.||...  .|:.
Human   260 ATGMIIMDGVEVPEENVL------------------PGASSLGGPFGCLNNARYGIAWGVLGASE 306

  Fly   319 LCSAAVIAVRYSAVRKQFGPERHGEEMAILEYQLHQYRIFPYLAA------ACVQKIATEELTST 377
            .|...  |.:|:..|.|||       :.:...||.|.::...|..      ||:|....::....
Human   307 FCLHT--ARQYALDRMQFG-------VPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKA 362

  Fly   378 YMEIIARSQADSNGFDVLTQNAAEIHALISSSKPLITWAARDAIQEAREACGGHGYLQAAKLGQM 442
            ..|:::..:.::.|                        .|.|..::||:..||:|......:.:.
Human   363 APEMVSLLKRNNCG------------------------KALDIARQARDMLGGNGISDEYHVIRH 403

  Fly   443 RTDHDPLCTYEGDNNV 458
            ..:.:.:.||||.:::
Human   404 AMNLEAVNTYEGTHDI 419

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.