Protein Alignment fon and NUP100

DIOPT Version :10

• Sequence 1: NP_609959.1
• Gene: fon / 35211
• FlyBaseID: FBgn0032773
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_012855.1
• Gene: NUP100 / 853796
• SGDID: S000001551
• Length: 959
• Species: Saccharomyces cerevisiae
• Alignment Length: 617
• Identity: 157/617 - (25%)
• Similarity: 218/617 - (35%)
• Gaps: 219/617 - (35%)

  Fly    16 GDFQQSLGRTKRDSFHSRHYSTHGQAVEQARKNAGYGGGYS-GSFGAGVDGASAQVDDSALGKLE 79
            |.|.||:|.|:...|.|.:.|       .|.....:||..| ||||...:.|.....:|
Yeast    77 GAFGQSMGATQNSPFGSLNSS-------NASNGNTFGGSSSMGSFGGNTNNAFNNNSNS------ 128

  Fly    80 SSYDSVGATESAEGASAGGLGGAVETLGG-----SAGTNTIGAGVGSS-------FGSNFASGFG 132
                    |.|..|.:....||   ||.|     ||||:::..|..:|       .||:|.:|..
Yeast   129 --------TNSPFGFNKPNTGG---TLFGSQNNNSAGTSSLFGGQSTSTTGTFGNTGSSFGTGLN 182

  Fly   133 GQNAASFGA-----QNAAG--FGAQNAASFGAQN--AASFG-SSFSSNAAFQTSS---ASNFGST 184
            |..:..|||     .|..|  ||.|.:::||..|  .:.|| .|.::|.||...:   .|:|||
Yeast   183 GNGSNIFGAGNNSQSNTTGSLFGNQQSSAFGTNNQQGSLFGQQSQNTNNAFGNQNQLGGSSFGS- 246

  Fly   185 AAHQVGSNVEFADNANA-GNKVD-----FGGVNAVD--SSAQLLSGVQTVQSVPTSEYYRHEKIV 241
              ..|||...|..:.|. ||..:     ||.:|:.:  ||...|.|..::.|
Yeast   247 --KPVGSGSLFGQSNNTLGNTTNNRNGLFGQMNSSNQGSSNSGLFGQNSMNS------------- 296

  Fly   242 STPQQVVYTIPGGSQRYVHHEERIVEQPTQVTQTVPVQTAHYYQRKVTTTASAPQLVQPVASSRL 306
                                          .||.|..|..:..|
Yeast   297 ------------------------------STQGVFGQNNNQMQ--------------------- 310

  Fly   307 TYGSNAASTFG-----SNAASN--FGSN----AATNFGSNAATNFGSNAAF--NSQ-----FGSS 353
            ..|:|..|.||     ||:||.  ||.|    .:..||.|:.|: ||:..|  |:|     |..|
Yeast   311 INGNNNNSLFGKANTFSNSASGGLFGQNNQQQGSGLFGQNSQTS-GSSGLFGQNNQKQPNTFTQS 374

  Fly   354 ------YGQNFQQNSQLSQLL---------------SQTQ---------------QAARQQAALQ 382
                  :|||..|..|.:.|.               |.||               |:.:..:...
Yeast   375 NTGIGLFGQNNNQQQQSTGLFGAKPAGTTGSLFGGNSSTQPNSLFGTTNVPTSNTQSQQGNSLFG 439

  Fly   383 AASANQVQAGSGYAAGSQGGFNS--GYNSAFNSGSQFGFNSASSL---------NSASSLNSAST 436
            |.....:..|....|...|..||  |...|..:||.||.|:||:.         |:|:  ||.||
Yeast   440 ATKLTNMPFGGNPTANQSGSGNSLFGTKPASTTGSLFGNNTASTTVPSTNGLFGNNAN--NSTST 502

  Fly   437 GN-----------SAALLSGSLLGGSQGSLLSGQVGGQQSLLSGSLLSGQQNLGL----GLNAA- 485
            .|           |...|.|.|.|.|..:  |..:|..:.:..|:    .||.||    |.|::
Yeast   503 TNTGLFGAKPDSQSKPALGGGLFGNSNSN--SSTIGQNKPVFGGT----TQNTGLFGATGTNSSA 561

  Fly   486 --QTGQVVGASSVGAGLSAGAGNLGSGYRTKQ 515
              .||::.|.::  ..|:.|..|:.....|.|
Yeast   562 VGSTGKLFGQNN--NTLNVGTQNVPPVNNTTQ 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fon	NP_609959.1	None
NUP100	NP_012855.1	FhaB	<54..647	CDD:442443	157/617 (25%)
		Nucleoporin2	814..955	CDD:461171