Protein Alignment fon and Nup98

DIOPT Version :9

• Sequence 1: NP_001163013.1
• Gene: fon / 35211
• FlyBaseID: FBgn0032773
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_112336.2
• Gene: Nup98 / 81738
• RGDID: 71033
• Length: 1816
• Species: Rattus norvegicus
• Alignment Length: 526
• Identity: 123/526 - (23%)
• Similarity: 196/526 - (37%)
• Gaps: 131/526 - (24%)

  Fly    36 STHGQAVEQARKNAGYGGGYSGSFGAGVDGASAQVDDSALGKLESSYDSVGATESAEGASAGGLG 100
            ||.||       |.|:|....|:||....|:|                          .:.|||.
  Rat    21 STFGQ-------NTGFGTTSGGAFGTSAFGSS--------------------------NNTGGLF 52

  Fly   101 GAVETL-GGSAGTNTI---------GAGVGSSFG-SNFASGFGGQNAASFGAQNAAGFGAQNAAS 154
            |..:|. ||..||::.         |.|.|:|.| ||...|......:.|.:||.| |.......
  Rat    53 GNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTANTGTSLFSSQNNA-FAQNKPTG 116

  Fly   155 FGAQNAASFGSSFSSNAAFQTSSASN--FGSTAAHQVGSNVEFADNANAGNKVDFGGVNAVDSSA 217
            ||     :||:|.||...|.|::.::  ||:|:....|.:...|  |..|..:.|......|:..
  Rat   117 FG-----NFGTSTSSGGLFGTTNTTSNPFGNTSGSLFGPSSFTA--APTGTTIKFNPPTGTDTMV 174

  Fly   218 QLLSGVQTVQSVPTSEYYRHEKIVSTPQQVVYTIPGGSQRYVHHEERIVEQPTQVTQTVPVQTAH 282
            :  :||.|              .:||..|.:..:.       .:|.:.:|:         ::...
  Rat   175 K--AGVST--------------NISTKHQCITAMK-------EYESKSLEE---------LRLED 207

  Fly   283 YYQRKVTTTASAPQLVQPVASSRLTYGSNAASTFGSNAASNFGSNAATNFGSNAATNFG-SNAAF 346
            |...:     ..||......::...:||:.|::..:...|:..:|:|.::|.| .|.|| |...|
  Rat   208 YQANR-----KGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSAFSYGQN-KTAFGTSTTGF 266

  Fly   347 NSQFGSSYGQNFQQNSQLSQLLSQ----------TQQAARQQAALQAASANQVQAGSGYAAGSQG 401
            .:..|..:|   |||.|.:.|.|:          |..:....:.|...|.|.:.......|...|
  Rat   267 GTNPGGLFG---QQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTMGLFGVTQASQPG 328

  Fly   402 GF-----NSGYNSAFNSGS------QFGFNS-ASSLNSASSLNSASTGNSAALLSGSLLGGSQGS 454
            |.     |:...:||.:|:      ..||.: .|:|...:.|.:..|..::|...|:..||
  Rat   329 GLFGTATNTSTGTAFGTGTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGG---- 389

  Fly   455 LLSGQVGGQQSLLSGSLLSGQQNLGLGLNAAQT---GQVVGASSVGAGLSAGAGN-LGSGYRTKQ 515
                 :.|.:..|:....:...|.|.|.|.:.:   |....|.::|.||..|.|. ||:|..:..
  Rat   390 -----LFGNKPTLTLGTNTNTSNFGFGTNNSGSSIFGSKPAAGTLGTGLGTGFGTALGAGQASLF 449

  Fly   516 WEKQSK 521
            ...|.|
  Rat   450 GNNQPK 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fon	NP_001163013.1	None
Nup98	NP_112336.2	FG repeats 1	1..156		48/175 (27%)
		Nucleoporin_FG	25..149	CDD:290362	43/162 (27%)
		NupH_GANP	26..336	CDD:293373	87/384 (23%)
		GLEBS, interaction with RAE1. /evidence=ECO:0000250	157..213		12/92 (13%)
		FG repeats 2	214..480		62/255 (24%)
		Nucleoporin_FG	215..303	CDD:290362	24/91 (26%)
		Nucleoporin_FG	261..392	CDD:290362	31/142 (22%)
		Nucleoporin2	740..880	CDD:282016
		Nup96	1333..1624	CDD:288926

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0845
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900