Protein Alignment fon and NCOA5

DIOPT Version :10

• Sequence 1: NP_609959.1
• Gene: fon / 35211
• FlyBaseID: FBgn0032773
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_066018.1
• Gene: NCOA5 / 57727
• HGNCID: 15909
• Length: 579
• Species: Homo sapiens
• Alignment Length: 206
• Identity: 47/206 - (22%)
• Similarity: 73/206 - (35%)
• Gaps: 27/206 - (13%)

  Fly   370 QTQQAARQQAALQAASANQVQAGSGYAAGSQGGFNSGYNSAFNSGSQFGFNSASSLNS------- 427
            :.::.|||.|.:...:..|.:...|...|.:||......|..|..:...:.:|...:.
Human   305 EREEIARQAAKMADEAILQERERGGPEEGVRGGHPPAIQSLINLLADNRYLTAEETDKIINYLRE 369

  Fly   428 -ASSLNSASTGNSAALLSGSLLGGSQGSLLSGQVGGQQSLLSGSLL-----------SGQQNLGL 480
             ...|..:||.:....:|...||.:.|:.|..| ...|.|.||.:|           :.||.|..
Human   370 RKERLMRSSTDSLPGPISRQPLGATSGASLKTQ-PSSQPLQSGQVLPSATPTPSAPPTSQQELQA 433

  Fly   481 GLNAAQTGQVVGASSVGAGLSAGAGNLGSGYRTKQWEKQSKWSSQNSYDSNGHVNNYKDLVTGES 545
            .:.:......|.|:|..|..|..|||..:...:.....|.:..||.|       .|....:.|:.
Human   434 KILSLFNSGTVTANSSSASPSVAAGNTPNQNFSTAANSQPQQRSQAS-------GNQPPSILGQG 491

  Fly   546 ESVDINGKRAG 556
            .|....|.|.|
Human   492 GSAQNMGPRPG 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fon	NP_609959.1	None
NCOA5	NP_066018.1	Transcription repression	1..158
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..78
		PRK12678	<32..>135	CDD:237171
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	148..173
		LXXLL motif	345..349		1/3 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	375..428		13/53 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	444..537		18/66 (27%)
		Transcription activation	458..579		12/52 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	560..579