DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fon and Ncoa5

DIOPT Version :9

Sequence 1:	NP_001163013.1	Gene:	fon / 35211	FlyBaseID:	FBgn0032773	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_659141.1	Gene:	Ncoa5 / 228869	MGIID:	2385165	Length:	579	Species:	Mus musculus

Alignment Length:	180	Identity:	50/180 - (27%)
Similarity:	66/180 - (36%)	Gaps:	63/180 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   268 QPTQVTQTVPVQTAHYYQRKVTTTASAPQLVQPVASSRLTYGSNAASTFGSNAASNFGSNAATNF 332
            ||.|..|.:|         ..|.|.:||...|....:::      .|.|.|.|.:...|:|:.:.
Mouse   406 QPLQSGQVLP---------SATPTPAAPPTSQQELQAKI------LSLFNSGAVAANSSSASPSV 455

  Fly   333 GSNAATNFGSNAAFNSQFGSSYGQNFQQNSQLSQLLSQTQQAARQQAALQAASANQV-----QAG 392
            .:                |||..|||...:.     ||.||  |.|     ||.||.     |||
Mouse   456 AT----------------GSSQNQNFSTAAN-----SQPQQ--RPQ-----ASGNQPPNIVGQAG 492

  Fly   393 SGYAAGSQGGFNSGYNSAFNSGSQFGFNSASS-LNSASSLNS----ASTG 437
            |....|.:.|          :.||..|...|| |..||::.|    :|||
Mouse   493 SARNMGPRPG----------APSQGLFGQPSSRLAPASTMASQRPVSSTG 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fon	NP_001163013.1	None
Ncoa5	NP_659141.1	Transcription repression	1..158
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..77
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	148..172
		HisS	<186..256	CDD:223202
		LXXLL motif	345..349
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	378..428		9/30 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	446..529		33/120 (28%)
		Transcription activation	458..579		34/97 (35%)
		PRK14971	<459..>543	CDD:237874	33/96 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0845
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900