Protein Alignment fon and npp-4

DIOPT Version :10

• Sequence 1: NP_609959.1
• Gene: fon / 35211
• FlyBaseID: FBgn0032773
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_493552.1
• Gene: npp-4 / 173329
• WormBaseID: WBGene00003790
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 106/553 - (19%)
• Similarity: 172/553 - (31%)
• Gaps: 167/553 - (30%)

  Fly    39 GQAVEQARKNAGYGGGYSGSFGAGVDG--------ASAQVDDSALGKLESSYDSV---GATESAE 92
            |.....|.|..|..|..:.:..:|:.|        |||.:..|......:|..||   |:|.:..
 Worm    20 GSTAAAAPKPGGLFGAPAAAMSSGLFGASQTAPAPASAGLFGSTTAPTPASTSSVPLFGSTTTTA 84

  Fly    93 GASAGGLGGAVET------LGGSAGTNTIGAGVGSSFGSNF-ASG--FGGQNAAS---------F 139
            ..|.|..|....|      .||..|.:|.....||.|||.. |:|  ||.::..|         |
 Worm    85 SPSGGLFGAKTATTAAPAPTGGLFGASTAAPATGSLFGSTAPATGGLFGAKSTTSAAPTLGGGLF 149

  Fly   140 GAQNA------AGFGAQNAASF------GAQNAASFGSSFSSNAAFQTSSASNFG-STAAHQVG- 190
            |:..|      ..|||..|.:.      |.|...|.|....:.:...|||.:..| |..|.:.|
 Worm   150 GSSTAPAAAATTSFGAPPATAAAPLGLGGIQQQNSSGGGLPNASGTATSSLTGTGDSKDASKDGE 214

  Fly   191 --------------------SNVEFADNANAGNKVDFGGVNAVDSSAQLLSGVQTVQSVPTSEYY 235
                                .|.||.:.....:..:......:|.:...:..|:......|....
 Worm   215 WTQAATLIRDLLPLIEDKFKKNREFMEETENMSIDNVAIEEQIDKTRGWIEEVRRDVLTATQSSE 279

  Fly   236 RHEKIVSTPQQVVYTIPGGSQRYVHHE-------------------------------------- 262
            |...:|||.:    |:...::|...|.
 Worm   280 RIAYLVSTDK----TLCDTTKRVQEHSGSANQTTYMNAIKEHLAELCNFYGNDMDALQERVNFLR 340

  Fly   263 ---ERIVEQPTQVTQ----------TVPVQTAHYYQRKVTTTASAPQLVQPVASSRLTYGSNAAS 314
               |:::.....:|.          ...|..||::   ||.....   ::.:....:..|.....
 Worm   341 NRFEKLLTGEKSITMEELDAYFLRCDANVSNAHHH---VTELGKE---IEEIRDFLIEQGYTQLR 399

  Fly   315 TFGSNAASNFGSNAATNFGSNAATNFGSNAAFNSQFGSSYGQNFQQNSQLSQLLSQTQQAARQQA 379
            .:.:.|||             ||....||:....:.|:.:   |...|.|:.:.|..:..|....
 Worm   400 KWSTTAAS-------------AAAPIASNSEMIVREGAEF---FPSQSSLAIIGSSLRAPAAPAP 448

  Fly   380 ALQAASANQVQAGSGYAAGSQGGFNSGYNS---------AFNSGSQFGFNSASSLNSASSLNSAS 435
            |:         .|.|...|:....|:|..|         ||:.||.||..::::.:||::..:..
 Worm   449 AV---------GGLGLGTGTSLFGNTGTTSLFGSTATKPAFSGGSLFGATTSTATSSAAATTTTP 504

  Fly   436 T---------GNSAALLSGSLLGGSQGSLLSGQ 459
            |         ..:....:.::...|.|.|.|.:
 Worm   505 TTSLFGSTKPATTTTPFASTVANNSSGLLFSSK 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fon	NP_609959.1	None
npp-4	NP_493552.1	Nucleoporin_FG	2..92	CDD:463941	18/71 (25%)
		Nucleoporin_FG	58..150	CDD:463941	24/91 (26%)
		SMC_prok_B	<216..386	CDD:274008	20/179 (11%)