DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dnt and KIN1

DIOPT Version :9

Sequence 1:	NP_001260567.1	Gene:	dnt / 35207	FlyBaseID:	FBgn0024245	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_010407.1	Gene:	KIN1 / 851700	SGDID:	S000002529	Length:	1064	Species:	Saccharomyces cerevisiae

Alignment Length:	326	Identity:	69/326 - (21%)
Similarity:	132/326 - (40%)	Gaps:	84/326 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 VSVEQQHPEELHRRISELTVERCRVRLSSL--------LQEGTFGRVYRGTYNDTQDV-LVKTVA 348
            ||..|..|::.||:              ||        :..|:.|:|....:..|.:| .||.|.
Yeast   102 VSSSQGMPKQFHRK--------------SLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVN 152

  Fly   349 Q------HASQM-------QVLLLLQE------------------GMLLYGASHPGILSVLGV-S 381
            :      |..||       |.:|..|:                  |.:||   ||.|..:..: :
Yeast   153 RATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILY---HPHICRLFEMCT 214

  Fly   382 IEDHTTPFVLYPALNNTRNLKQFLLDPACAR-TVTTIQIVMMASQLSMALDHLHSHGVVHKDIAT 445
            :.:|.  ::|:..::..:     |||..... ::...|....|..::.||.:||::.:||:|:..
Yeast   215 LSNHF--YMLFEYVSGGQ-----LLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKI 272

  Fly   446 RNCVIDDQLRVKLSDSSLSRDLFPSDYNCLGDSENR------PVKWMSLEALQHKQFSEAS-DSW 503
            .|.:|.|...:|:.|..||.         :.||..:      .:.:.:.|.|:...::... |.|
Yeast   273 ENIMISDSSEIKIIDFGLSN---------IYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVW 328

  Fly   504 AFGVLMWELCTSAKQPYAEVDPFEMEHYLKDGYRLAQPFNCPDELFTIMAYCWALLPAERPTFAQ 568
            :|||:::.| ...|.|:.:.:...:...:|.| ::..|.:...|:.::::....:.|..|.|..|
Yeast   329 SFGVVLFVL-VCGKVPFDDENSSVLHEKIKQG-KVEYPQHLSIEVISLLSKMLVVDPKRRATLKQ 391

  Fly   569 L 569
            :
Yeast   392 V 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dnt	NP_001260567.1	WIF	46..182	CDD:128745
		PKc_like	310..580	CDD:304357	63/309 (20%)
		Pkinase_Tyr	317..573	CDD:285015	63/302 (21%)
KIN1	NP_010407.1	STKc_Kin1_2	118..398	CDD:270979	61/296 (21%)
KIN1	NP_010407.1	MARK_C_like	890..1062	CDD:213377
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000