Protein Alignment dnt and Eph

DIOPT Version :9

• Sequence 1: NP_001260567.1
• Gene: dnt / 35207
• FlyBaseID: FBgn0024245
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_524625.3
• Gene: Eph / 43803
• FlyBaseID: FBgn0025936
• Length: 1096
• Species: Drosophila melanogaster
• Alignment Length: 600
• Identity: 129/600 - (21%)
• Similarity: 241/600 - (40%)
• Gaps: 118/600 - (19%)

  Fly    35 LQLHSGSEVAAHLNVF----------------------LN-PVEVMRLLGVSAEVYYVREGHINN 76
            :|:|:.:.| :|:|.|                      || |:::..:....||:.:..|..:.:
  Fly   469 VQIHAINSV-SHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLS 532

  Fly    77 YALNFIVPVPANVKDISFTWQSLAGRGLPYSINVV----SSDQEVLPRPAINVSHS-----GEIP 132
            ...|..:....| ||....|........|.....|    ..:.:.:.:.|:|...:     |.:.
  Fly   533 TVFNLRILAITN-KDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLE 596

  Fly   133 TTIQTWSIALKCSGLKAAEVDVTVSLEVVLNRSLNNVTHLVFRRKKICLMNDSAEDLSEDVDDPQ 197
            .|  .:...::|.                .|....:.:::::.:        :.:.:....||..
  Fly   597 NT--EYGFQVRCK----------------TNNGFGSYSNMIYAQ--------TLQSVGSVYDDSV 635

  Fly   198 LLETVMLPPTGLITLVVGVSVAMGSVCLLLMIAYCVKGAANKRQHHQHGGQPMRTSSFQRLNTHP 262
            .:..:    .|.|  |.||         |.::.:.:......|..||.......|:       |.
  Fly   636 QIRFI----AGAI--VTGV---------LFLVIFIIATVYFMRSKHQDDLDKKSTN-------HL 678

  Fly   263 PC----QSSMGSAAYMTP-------SIIAPIHGSSLPRKVPVSVEQQHPEELHRRISELTVERCR 316
            |.    .|:..::...||       ::..|:.|:|.....|.:.|.  |.:..|..:. .::...
  Fly   679 PLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYED--PNQAIREFAR-EIDANY 740

  Fly   317 VRLSSLLQEGTFGRVYRGTY----NDTQ--DVLVKTVAQHASQMQVLLLLQEGMLLYGASHPGIL 375
            :.:.:::..|.||.|.||..    |..|  ||.:||:...:|:......|.|..::....||.::
  Fly   741 ITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVI 805

  Fly   376 SVLGVSIEDHTTPFVLYPALNNTRNLKQFLLDPACART----VTTIQIVMMASQLSMALDHLHSH 436
            .:.||  ...:.|.::........:|..||      |.    ..|:|:::|...::..:.:|...
  Fly   806 YLQGV--VTRSNPVMIITEYMENGSLDTFL------RVNDGKFQTLQLIVMLRGIASGMSYLSDM 862

  Fly   437 GVVHKDIATRNCVIDDQLRVKLSDSSLSRDL-FPSD-YNCLGDSENRPVKWMSLEALQHKQFSEA 499
            ..||:|:|.||.:::.||..|::|..|||:: ..|| |...|.  ..||:|.:.||:..::|:.|
  Fly   863 NYVHRDLAARNVLVNAQLICKIADFGLSREIENASDAYTTRGG--KIPVRWTAPEAIAFRKFTSA 925

  Fly   500 SDSWAFGVLMWELCTSAKQPYAEVDPFEMEHYLKDGYRLAQPFNCPDELFTIMAYCWALLPAERP 564
            ||.|::||::||:.:..::||......::...::.||||..|.:||:.|:.:|..||......||
  Fly   926 SDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRP 990

  Fly   565 TFAQLQSCLSEFYSQ 579
            |||.:.|.|.....|
  Fly   991 TFASIVSTLDNLARQ 1005

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnt	NP_001260567.1	WIF	46..182	CDD:128745	22/167 (13%)
		PKc_like	310..580	CDD:304357	79/281 (28%)
		Pkinase_Tyr	317..573	CDD:285015	78/267 (29%)
Eph	NP_524625.3	EphR_LBD	85..260	CDD:198439
		FN3	387..476	CDD:238020	2/6 (33%)
		FN3	536..623	CDD:238020	13/113 (12%)
		EphA2_TM	644..736	CDD:291255	21/112 (19%)
		PTKc_EphR	736..1002	CDD:270629	79/275 (29%)
		Pkinase_Tyr	741..999	CDD:285015	78/267 (29%)
		SAM_1	1033..1092	CDD:278937
		SAM	1039..1092	CDD:197735

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455344
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940