Protein Alignment dnt and insra

DIOPT Version :10

• Sequence 1: NP_477341.2
• Gene: dnt / 35207
• FlyBaseID: FBgn0024245
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_073767884.1
• Gene: insra / 245699
• ZFINID: ZDB-GENE-020503-3
• Length: 1386
• Species: Danio rerio
• Alignment Length: 483
• Identity: 128/483 - (26%)
• Similarity: 203/483 - (42%)
• Gaps: 120/483 - (24%)

  Fly   123 INVSHSGEIPTTIQTWSIALKCSGLKAAEVDVTVSLEVVLNRSLNNVTHLVFRRKKICLMNDSAE 187
            :.|.|.|.....|:..|:|    |                |.|....||..            .:
Zfish   923 LRVVHPGNYTVRIRATSLA----G----------------NGSWTEPTHFY------------VQ 955

  Fly   188 DLSEDVDDPQLLETVMLPPTGLITLVVGVSVAMGSVCLLLMIAYCVKG--AANKRQHHQHGGQPM 250
            ||..|             |:.::.:|:|     ..:|..|::..|| |  ...|:|.....|
Zfish   956 DLRVD-------------PSNVLKIVIG-----PVICFFLLLLLCV-GFYIVKKKQTEGPTG--- 998

  Fly   251 RTSSFQRLNTHPPCQSSMGSAAYMTPSIIAPIHGSSLPRKVPVSVEQQHPEELHRRISELTVERC 315
                  ||.|.|       :..|.:|.                  |...|:|..       |.|.
Zfish   999 ------RLYTSP-------NPEYFSPD------------------EVYEPDEWE-------VPRE 1025

  Fly   316 RVRLSSLLQEGTFGRVYRGTYND------TQDVLVKTVAQHASQMQVLLLLQEGMLLYGASHPGI 374
            ::.|...|.:|:||.||.|...|      ...|.||||.:.||..:.:..|.|..::...|...:
Zfish  1026 KITLLRELGQGSFGMVYEGNGKDIVKGESQTRVAVKTVNESASLRERIEFLNEASVMKAFSCHHV 1090

  Fly   375 LSVLGVSIEDHTTPFVLYPALNNTRNLKQFL--LDPAC----ARTVTTI-QIVMMASQLSMALDH 432
            :.:|||..:...|..|:  .|....:||.||  |.|..    .|...|: :::.||::::..:.:
Zfish  1091 VRLLGVVSKGQPTLVVM--ELMTHGDLKSFLRSLRPDSENNPGRPPPTLKEMIQMAAEIADGMAY 1153

  Fly   433 LHSHGVVHKDIATRNCVIDDQLRVKLSDSSLSRDLFPSDYNCLGDSENRPVKWMSLEALQHKQFS 497
            |::...||:|:|.|||::.:.|.||:.|..::||::.:||...|.....||:||:.|:|:...|:
Zfish  1154 LNAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFT 1218

  Fly   498 EASDSWAFGVLMWELCTSAKQPYAEVDPFEMEHYLKDGYRLAQPFNCPDELFTIMAYCWALLPAE 562
            ..||.|:|||::||:.|.|:|||..:...::..::.:|..|.:|.||.|.|..:|..||...|..
Zfish  1219 AHSDCWSFGVVLWEVSTLAEQPYQGLSNEQVLKFVMEGGYLDRPDNCADRLHNLMQMCWHYNPKM 1283

  Fly   563 RPTFAQLQSCLSE-----------FYSQ 579
            ||||.::...|.|           |||:
Zfish  1284 RPTFQEIIEMLREDLHPSFQEVSFFYSE 1311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnt	NP_477341.2	WIF	46..182	CDD:128745	11/58 (19%)
		Protein Kinases, catalytic domain	310..580	CDD:473864	94/294 (32%)
insra	XP_073767884.1	None