| Sequence 1: | NP_001260567.1 | Gene: | dnt / 35207 | FlyBaseID: | FBgn0024245 | Length: | 584 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001003817.1 | Gene: | Erbb2 / 13866 | MGIID: | 95410 | Length: | 1256 | Species: | Mus musculus |
| Alignment Length: | 413 | Identity: | 100/413 - (24%) |
|---|---|---|---|
| Similarity: | 163/413 - (39%) | Gaps: | 108/413 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 205 PPTGLITLVVGVSVAMGSVCLLLMIAYCVKGAANKRQHHQHGGQPMRTSSFQRLNTHPPCQSSMG 269
Fly 270 SAAYMTPSIIAPIHGSSLPRKVPVSVEQQHPEELHRRISELTVERCRVRLSSLLQEGTFGRVYRG 334
Fly 335 TY-----NDTQDVLVKTVAQHASQMQVLLLLQEGMLLYGASHPGILSVLGVSIEDHTTPFVLYPA 394
Fly 395 LNNTRNLKQFLLDPACARTVTTIQIVMMASQLSMALDHLHSH----------------------- 436
Fly 437 ---GVVHKDIATRNCVIDDQLRVKLSDSSLSR--DLFPSDYNCLGDSENRPVKWMSLEALQHKQF 496
Fly 497 SEASDSWAFGVLMWELCTSAKQPYAEVDPFEMEHYLKDGYRLAQPFNCPDELFTIMAYCWALLPA 561
Fly 562 ERPTFAQLQSCLSEFYSQITRYV 584 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| dnt | NP_001260567.1 | WIF | 46..182 | CDD:128745 | |
| PKc_like | 310..580 | CDD:304357 | 75/302 (25%) | ||
| Pkinase_Tyr | 317..573 | CDD:285015 | 74/288 (26%) | ||
| Erbb2 | NP_001003817.1 | Recep_L_domain | 52..174 | CDD:279382 | |
| Furin-like | 190..339 | CDD:279142 | |||
| FU | 236..281 | CDD:238021 | |||
| Recep_L_domain | 367..487 | CDD:279382 | |||
| GF_recep_IV | 511..644 | CDD:291509 | |||
| FU | 512..>545 | CDD:238021 | |||
| FU | 558..604 | CDD:214589 | |||
| TM_ErbB2 | 642..685 | CDD:213055 | 15/46 (33%) | ||
| Nuclear localization signal. /evidence=ECO:0000250 | 677..690 | 4/17 (24%) | |||
| Required for interaction with KPNB1 and EEA1. /evidence=ECO:0000250 | 677..690 | 4/17 (24%) | |||
| PTKc_HER2 | 713..991 | CDD:270684 | 79/313 (25%) | ||
| Pkinase_Tyr | 721..977 | CDD:285015 | 74/288 (26%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1030..1180 | ||||
| Interaction with PIK3C2B. /evidence=ECO:0000250 | 1196..1198 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1200..1219 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1224..1256 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1025 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||