| Sequence 1: | NP_001260567.1 | Gene: | dnt / 35207 | FlyBaseID: | FBgn0024245 | Length: | 584 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_997538.1 | Gene: | Egfr / 13649 | MGIID: | 95294 | Length: | 1210 | Species: | Mus musculus |
| Alignment Length: | 512 | Identity: | 109/512 - (21%) |
|---|---|---|---|
| Similarity: | 202/512 - (39%) | Gaps: | 124/512 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 104 LPYSINVVSSDQEVLPRPAINVSHSGEIPTTIQT-------------WSIALKCSGLKAAEVDVT 155
Fly 156 VSLEVVLNRSLNNVTHLVFRRKKICLMNDSAEDLSEDVDDPQLLETVMLPPTG--LITLVVGVSV 218
Fly 219 AMGSVCLLLMIAYCVKGAANKRQHHQHGGQPMRTSSFQRLNTHPPCQSSMGSAAYMTPSIIAPIH 283
Fly 284 GSSLPRKVPVSVEQQHPEELHRRI-SELTVERCRVRLSSLLQEGTFGRVYRGTYNDTQD-----V 342
Fly 343 LVKTVAQHASQMQVLLLLQEGMLLYGASHPGILSVLGVSIEDHTTPFV--LYP---ALNNTRNLK 402
Fly 403 -----QFLLDPACARTVTTIQIVMMASQLSMALDHLHSHGVVHKDIATRNCVIDDQLRVKLSDSS 462
Fly 463 LSRDLFPSDYNCLGDSENRPVKWMSLEALQHKQFSEASDSWAFGVLMWELCTSAKQPYAEVDPFE 527
Fly 528 MEHYLKDGYRLAQPFNCPDELFTIMAYCWALLPAERPTFAQLQSCLSEFYSQITRYV 584 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| dnt | NP_001260567.1 | WIF | 46..182 | CDD:128745 | 16/90 (18%) |
| PKc_like | 310..580 | CDD:304357 | 72/284 (25%) | ||
| Pkinase_Tyr | 317..573 | CDD:285015 | 71/270 (26%) | ||
| Egfr | NP_997538.1 | Recep_L_domain | 57..168 | CDD:279382 | |
| Approximate | 75..300 | ||||
| Furin-like | 184..335 | CDD:279142 | |||
| FU | 231..274 | CDD:238021 | |||
| Recep_L_domain | 362..481 | CDD:279382 | |||
| Approximate | 390..600 | 8/38 (21%) | |||
| GF_recep_IV | 505..636 | CDD:291509 | 17/110 (15%) | ||
| FU | 506..559 | CDD:238021 | |||
| FU | 552..598 | CDD:214589 | 8/36 (22%) | ||
| TM_ErbB1 | 634..679 | CDD:213054 | 9/54 (17%) | ||
| Important for dimerization, phosphorylation and activation. /evidence=ECO:0000250 | 690..706 | 3/26 (12%) | |||
| PTKc_EGFR | 706..1018 | CDD:270683 | 77/296 (26%) | ||
| TyrKc | 715..970 | CDD:197581 | 71/274 (26%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1113..1137 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1025 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||