DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dnt and WIF1

DIOPT Version :9

Sequence 1:	NP_001260567.1	Gene:	dnt / 35207	FlyBaseID:	FBgn0024245	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_009122.2	Gene:	WIF1 / 11197	HGNCID:	18081	Length:	379	Species:	Homo sapiens

Alignment Length:	158	Identity:	39/158 - (24%)
Similarity:	73/158 - (46%)	Gaps:	17/158 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 MWVLS-LLALAALQLHSGSEVAAHLNVFLNPVEVMRLLGVSAEVYYVREGHINNYALNF------ 81
            :|:.| ||.|.||:..:|......|.::::..:...|:|...::..|.||.:..:..:|
Human    12 LWLWSILLCLLALRAEAGPPQEESLYLWIDAHQARVLIGFEEDILIVSEGKMAPFTHDFRKAQQR 76

  Fly    82 IVPVPANVKDISFTWQSLAGRGLPYS-INVVSSDQEVLPRPAINVSHSGEIPTTIQTWSIALKC- 144
            :..:|.|:..::||||:.......|. :::.|.|:.::..|.:||...|.:|.......:...|
Human    77 MPAIPVNIHSMNFTWQAAGQAEYFYEFLSLRSLDKGIMADPTVNVPLLGTVPHKASVVQVGFPCL 141

  Fly   145 ---SGLKAAEVDVTVSLEVVLNRSLNNV 169
               .|:.|.||||     :|:|...|.:
Human   142 GKQDGVAAFEVDV-----IVMNSEGNTI 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dnt	NP_001260567.1	WIF	46..182	CDD:128745	31/135 (23%)
		PKc_like	310..580	CDD:304357
		Pkinase_Tyr	317..573	CDD:285015
WIF1	NP_009122.2	WIF	35..179	CDD:128745	31/135 (23%)
WIF1	NP_009122.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	354..379
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000