Protein Alignment dnt and erbb4a

DIOPT Version :9

• Sequence 1: NP_001260567.1
• Gene: dnt / 35207
• FlyBaseID: FBgn0024245
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001137223.1
• Gene: erbb4a / 100007677
• ZFINID: ZDB-GENE-030918-4
• Length: 1414
• Species: Danio rerio
• Alignment Length: 503
• Identity: 111/503 - (22%)
• Similarity: 190/503 - (37%)
• Gaps: 138/503 - (27%)

  Fly   119 PRPAINVSHSGEIPTTIQTWSIALKC-SGLKAAEVDVTVSLEVVLNRSLNNVTHLVFRRKKICLM 182
            |...:...|..:.|..::      || .||:.|...:....|.      ||..|       .|..
Zfish   573 PDHCVKCLHLKDGPNCVE------KCPDGLQGANSFIFKYAET------NNECH-------PCHP 618

  Fly   183 NDSAEDLSEDVDDPQLLETV-MLPPTGLIT--LVVGVSVAMGSVCLLLMIAYCVKGAANKRQHHQ 244
            |     .::....|::.:.| ||..|.||.  |:.|:.|.   |.:.|.:|..::..:.|::.
Zfish   619 N-----CTQGCTGPRIQDCVGMLDRTPLIAAGLIGGLFVI---VIIALSVAVYIRRKSIKKKR-- 673

  Fly   245 HGGQPMRTSSFQRLNTHPPCQSSMGSAAYMTPSIIAPIHGSSLPRKVPVSVEQQHPEELHRRISE 309
                     :.:|               ::...::.|:..|...           |.:...||.:
Zfish   674 ---------ALRR---------------FLETELVEPLTPSGAA-----------PNQAQLRILK 703

  Fly   310 LTVERCRVRLSSLLQEGTFGRVYRGTYNDTQD-----VLVKTVAQHASQMQVLLLLQEGMLLYGA 369
            .| |..||:   :|..|.||.||.|.:....:     |.:|.:.:.......:..:.|.:::...
Zfish   704 ET-ELKRVK---ILGAGAFGMVYXGIWVPEGETVKIPVAIKILNESTGPKANVEFMDEALIMASM 764

  Fly   370 SHPGILSVLGVSIEDHTTPFVLYPALNNTRNLKQFLLDPACARTVTTIQIVMMASQLSMALDHLH 434
            .||.::.:|||                        .|.|       |||:|.........||::|
Zfish   765 EHPHLVRLLGV------------------------CLSP-------TIQLVTQLMPHGCLLDYVH 798

  Fly   435 SH--------------------------GVVHKDIATRNCVIDDQLRVKLSDSSLSR--DLFPSD 471
            .|                          .:||:.:|.||.::.....:|::|..|:|  |....:
Zfish   799 EHQDNIGSQLLLNWCVQIAKGMMXLEERRLVHRXLAARNVLVKSPNHIKITDFGLARLLDTDEKE 863

  Fly   472 YNCLGDSENRPVKWMSLEALQHKQFSEASDSWAFGVLMWELCTSAKQPYAEVDPFEMEHYLKDGY 536
            ||  .|....|:|||:||.:.:::|:..||.|::||.:|||.|....||..:...::...|:.|.
Zfish   864 YN--SDGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGXPYDGIPTRDIPDILEKGE 926

  Fly   537 RLAQPFNCPDELFTIMAYCWALLPAERPTFAQLQSCLSEFYSQITRYV 584
            ||.||..|..:::.:|..||.:....||.|.:|.:..|.......||:
Zfish   927 RLPQPPICTIDVYMVMVKCWMIDADSRPRFKELAAEFSRMARDPQRYL 974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnt	NP_001260567.1	WIF	46..182	CDD:128745	13/63 (21%)
		PKc_like	310..580	CDD:304357	75/302 (25%)
		Pkinase_Tyr	317..573	CDD:285015	71/288 (25%)
erbb4a	NP_001137223.1	Recep_L_domain	54..166	CDD:279382
		FU	182..216	CDD:214589
		Furin-like	184..331	CDD:279142
		FU	228..273	CDD:238021
		Recep_L_domain	357..477	CDD:279382
		GF_recep_IV	501..632	CDD:291509	15/82 (18%)
		FU	502..552	CDD:238021
		FU	548..595	CDD:214589	5/27 (19%)
		TM_ErbB4	631..674	CDD:213053	13/56 (23%)
		PKc_like	699..995	CDD:304357	79/313 (25%)
		Pkinase_Tyr	707..963	CDD:285015	72/291 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900