Protein Alignment CG10750 and CFAP73

DIOPT Version :10

• Sequence 1: NP_609955.1
• Gene: CG10750 / 35206
• FlyBaseID: FBgn0032769
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: XP_011536629.2
• Gene: CFAP73 / 387885
• HGNCID: 37100
• Length: 321
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 63/267 - (23%)
• Similarity: 123/267 - (46%)
• Gaps: 18/267 - (6%)

  Fly    33 QDQFFVKPPNWDSAGDNI-EMLYIANLRE--YDAMKQVQIQLLKDAKRQAALNVQRIRKMYKIQE 94
            |::...|.|  :.|.|:: .:|.:...|:  .||.:.:|.|......:.|||. ||..::.:.:.
Human    14 QEKLSTKLP--EQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALK-QRWEQLEQKER 75

  Fly    95 RLRKRFVEVNGFIKDCADKKRSADKSIREETVLHAEVTKEIDEFK--TSIAELSTFRNALKATVA 157
            .|:..|:..:.|::|...::..|.:...||.  |....:|::..:  |.:.||......|:..:.
Human    76 ELKGSFIRFDKFLQDSEARRNRALRRAAEER--HQAGRREVEALRLWTQLQELRREHARLQRRLK 138

  Fly   158 QFQPYERVLEEVVEVSDIFISTKDCIDRCDALMLAQVEINKLESQKLNEIEEMRLRMVQITSEAA 222
            :.:|..|:||:.:|:...|....:.:.|.|.|...|..:...|.::|.|:|..|.|:.|:.....
Human   139 RLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWP 203

  Fly   223 LTVLGLKNDLARLDRSYVSSRATCLKWE----KILSACKDTTSLYNLDKERMFDGIQILYRMLCK 283
            ..||......|:|.....::|...|:||    :|.:...:.|.|  |.:.||  .:..|::::|:
Human   204 DEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLL--LGRSRM--AVLNLFQLVCQ 264

  Fly   284 RRDIVPS 290
            .:...|:
Human   265 HQGQPPT 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10750	NP_609955.1	DUF4200	54..165	CDD:464003	24/114 (21%)
CFAP73	XP_011536629.2	Smc	<32..>269	CDD:440809	57/243 (23%)
		DUF4200	35..152	CDD:464003	27/119 (23%)