Protein Alignment pigeon and GSAP

DIOPT Version :10

• Sequence 1: NP_476946.1
• Gene: pigeon / 35200
• FlyBaseID: FBgn0010309
• Length: 915
• Species: Drosophila melanogaster
• Sequence 2: XP_011514627.1
• Gene: GSAP / 54103
• HGNCID: 28042
• Length: 872
• Species: Homo sapiens
• Alignment Length: 986
• Identity: 205/986 - (20%)
• Similarity: 374/986 - (37%)
• Gaps: 249/986 - (25%)

  Fly     2 LRQENLAANFCGLLASQGYKEKANEW---RILGQEQDGSLLTSWIFEYADEDQRKETCIGHFHAT 63
            ||.:...:...| ..|.|.....|::   .:|..|::|:::      |..:|.:.....|.:...
Human    19 LRAQRAVSEASG-AGSGGADVLENDYESLHVLNVERNGNII------YTYKDDKGNVVFGLYDCQ 76

  Fly    64 KKQLRLLWTLDNCREIVQATINSSVTLL--SFVEKT-EGKLYQ--------AFVVEVRSSEGGTA 117
            .:|..||:|.:...::...::||..|||  |.|:.| |||..:        ..:||:.
Human    77 TRQNELLYTFEKDLQVFSCSVNSERTLLAASLVQSTKEGKRNELQPGSKCLTLLVEIH------- 134

  Fly   118 TPLNS----EPSNRQMMTQFLW-RVESATRTCWQDKLLVLTHEESIKQYSCVVKQSSTTCSTGGG 177
             |:|:    :..:..:..|||: .:||  ....::.||:::.|:.|:|:...|.|.
Human   135 -PVNNVKVLKAVDSYIWVQFLYPHIES--HPLPENHLLLISEEKYIEQFRIHVAQE--------- 187

  Fly   178 EGSAWRLDTS-ILTYETLARNFSWAQWDPECQALYYIHLKPKAKSLSLLDEREEAGEQTTPTLSP 241
            :|:...:..| .|..:.:|.:|.|||||...|.||||.|| |::|:
Human   188 DGNRVVIKNSGHLPRDRIAEDFVWAQWDMSEQRLYYIDLK-KSRSI------------------- 232

  Fly   242 TLSAFQFNEKQPTETVLNIPLNLPKLPNGSKE-----ESPSYDDDAVPLRVHDSSLNLIILADTS 301
             |...||...:....:..:||::....:|.|.     :...|.|.      ....|.|.:..:.:
Human   233 -LKCIQFYADESYNLMFEVPLDISLSNSGFKLVNFGCDYHQYRDK------FSKHLTLCVFTNHT 290

  Fly   302 GMFFVCH--------------YYLYQ------PMQSEQRDVHFAYSVTLLHHGYVVHCVMPGVPW 346
            |...||:              :|:::      ....|....|....:|.|:..|.|...:||
Human   291 GSLCVCYSPKCASWGQITYSVFYIHKGHSKTFTTSLENVGSHMTKGITFLNLDYYVAVYLPG--- 352

  Fly   347 QKARLLRPTFALHGQHHLLVSSAFFVHLLDVGLQHEPN--CH-IVCAAHNRSPDITQLVPLRKW- 407
                                   .|.|||:|  || |:  || :....:|...|:....||:..
Human   353 -----------------------HFFHLLNV--QH-PDLICHNLFLTGNNEMIDMLPHCPLQSLS 391

  Fly   408 GALAYDAATLDLVSLSVPKSHLIEAFRNDSSLD-NRISIIHYFL------------------LHS 453
            |:|..|..:..|....:.:|.|::..:| :.|| .:::.:|..|                  |::
Human   392 GSLVLDCCSGKLYRALLSQSSLLQLLQN-TCLDCEKMAALHCALYCGQGAQFLEAQWRQRADLNT 455

  Fly   454 NDM--DVLAELLNNILERPLSLDTVALLKEALVAGSYAAAVRGLPEDAKPLMRLLPLTTALASRP 516
            |.:  |.| :::..|.|...:..:..|::|.::|.||.:..    .:...:.:|||
Human   456 NRVLSDFL-KIIQWISENVSACHSFDLIQEFIIASSYWSVY----SETSNMDKLLP--------- 506

  Fly   517 IHAKVADISVGLSHETLHNTSMMLLSPQQRLSPYRTDIWTRLWDLLN---ESAKQEQPRFS---- 574
             |:.|...:..:...||....:.|  |..::..::     ..|:.||   |..|..:|.|.
Human   507 -HSSVLTWNTEIPGITLVTEDIAL--PLMKVLSFK-----GYWEKLNSNLEYVKYAKPHFHYNNS 563

  Fly   575 ----------AEQVTEKLIFSLACYQPEALSRCTTPLSPDTGTGGFGDYSSGSAFPFSNEVLPFI 629
                      :|:.|.|.  ..|.|....|......:            |:..|......:.|.:
Human   564 VVRREWHNLISEEKTGKR--RSAAYVRNILDNAVKVI------------SNLEARNLGPRLTPLL 614

  Fly   630 ELEGCTASKQEHVISVYLRELSVHLVKHTSKPNTGFRWLKETFFERSQAPAHVHAVASQFVSAQL 694
            :.|.   |.|..::.:.:.||..|.::|...            .|:.:    :..:...::|..|
Human   615 QEED---SHQRLLMGLMVSELKDHFLRHLQG------------VEKKK----IEQMVLDYISKLL 660

  Fly   695 ELSRALCSLVCRAAGLDARMETSRGFQL-IDQMAANQQHSLFLILERYCLAVESIAFPLPEGFSS 758
            :       |:|.....:.|......:.| .:...:..:.::|.|:.|...|..|:..|||.||.:
Human   661 D-------LICHIVETNWRKHNLHSWVLHFNSRGSAAEFAVFHIMTRILEATNSLFLPLPPGFHT 718

  Fly   759 FFTYLGYRALGYDMFLQYVENHVFELQVDVMKAIVFDIEDSPLGIERKLSLLSALPKQRAQRLLK 823
            ..|.||.:.|.....|..:::.|..|....:..::.|::::....:.|.|::..||....|::.:
Human   719 LHTILGVQCLPLHNLLHCIDSGVLLLTETAVIRLMKDLDNTEKNEKLKFSIIVRLPPLIGQKICR 783

  Fly   824 CWQHPDSLMIRGREHAANILSGQQQEVLHQQRPTACVNQSRNNA--RSDLTAEALSPLDSFLDLL 886
            .|.||.|..|..|.|...:|...::             |.||:.  :|..:.|.| ||:.|:::|
Human   784 LWDHPMSSNIISRNHVTRLLQNYKK-------------QPRNSMINKSSFSVEFL-PLNYFIEIL 834

  Fly   887 TAKASLNELDY 897
            |...|.|:..|
Human   835 TDIESSNQALY 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pigeon	NP_476946.1	GSAP	28..515	CDD:438516	118/553 (21%)
		GSAP-16	694..807	CDD:464405	23/113 (20%)
GSAP	XP_011514627.1	GSAP	3..515	CDD:438516	126/593 (21%)
		GSAP-16	660..767	CDD:464405	23/113 (20%)