Protein Alignment gammaTub37C and TUBA1C

DIOPT Version :9

• Sequence 1: NP_001260565.1
• Gene: gammaTub37C / 35199
• FlyBaseID: FBgn0010097
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_001290043.1
• Gene: TUBA1C / 84790
• HGNCID: 20768
• Length: 519
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 140/448 - (31%)
• Similarity: 239/448 - (53%)
• Gaps: 31/448 - (6%)

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFAT--DGQDRKDVFFYQADDNHYIPRAVL 66
            |.|::.:||.|.|||...|:..||||||.|||.:....|  .|.|..:.||.:.....::||||.
Human    73 ECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVF 137

  Fly    67 IDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSD 130
            :||||.||:.:.|..|.:|::.|.:...|.  .|.||:|.| ::.|:::.:.|.|.:.:.||...
Human   138 VDLEPTVIDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIIDLVLDRIRKLADQCT 200

  Fly   131 SLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRL 195
            .|:||::.||..||||||..|.::||||..:.||....:|::| ..::|..||:|||||||....
Human   201 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYP-APQVSTAVVEPYNSILTTHTT 264

  Fly   196 TKCADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASL 260
            .:.:|...::||.|:..|....|.|:.||:|.:|.|:|.|:|..|.:||:...:|.:|.....:|
Human   265 LEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNL 329

  Fly   261 IPTPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQC------FV 319
            :|.|::||.:..|.|::|  ..|....:.||.::.....:|.|.||         :|      ::
Human   330 VPYPRIHFPLATYAPVIS--AEKAYHEQLTVAEITNACFEPANQMV---------KCDPRHGKYM 383

  Fly   320 SILNIIQGEVDPSQVHKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGL-----MM 379
            :...:.:|:|.|..|:.::..|:.::...|:.|.|...:|.:....|.|.....::.:     |:
Human   384 ACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCML 448

  Fly   380 ANHTGISSLFKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYE 437
            :|.|.::..:.|...::|.:..:.||:..:..|.|.:.:.:|   ||:.:..|.::||
Human   449 SNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE---AREDMAALEKDYE 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub37C	NP_001260565.1	PLN00222	1..447	CDD:215108	140/448 (31%)
		gamma_tubulin	4..436	CDD:276957	138/445 (31%)
TUBA1C	NP_001290043.1	PTZ00335	72..518	CDD:185562	140/448 (31%)
		alpha_tubulin	72..505	CDD:276955	140/448 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810