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Protein Alignment gammaTub37C and TUBB2A

DIOPT Version :10

Sequence 1:	NP_476922.1	Gene:	gammaTub37C / 35199	FlyBaseID:	FBgn0010097	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001060.1	Gene:	TUBB2A / 7280	HGNCID:	12412	Length:	445	Species:	Homo sapiens

Alignment Length:	439	Identity:	151/439 - (34%)
Similarity:	257/439 - (58%)	Gaps:	23/439 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFATDGQDRKDVFFYQADDNHYIPRAVLID 68
            ||:.:|.||||||||.:||:.:..||||.|.|.....:....:|.:|::.:|..|.|:|||:|:|
Human     3 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVD 67

  Fly    69 LEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSDSL 132
            |||..::::.:.|:.:::..:|....:  .|||||||.| :::|.::.:.|.|::.:|::..|.|
Human    68 LEPGTMDSVRSGPFGQIFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCL 130

  Fly   133 EGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRLTK 197
            :||.|.||:.||||||||:.::.::.|.:|.:::.|:||.|: .::||.||:|||:.|::.:|.:
Human   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPS-PKVSDTVVEPYNATLSVHQLVE 194

  Fly   198 CADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASLIP 262
            ..|....:||.||..|....|.:.|||:..:|:|||..||..||.||:|..:|.:|..|..:::|
Human   195 NTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 259

  Fly   263 TPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNIIQG 327
            .|:|||.|.|:.||.|  ......|..||.::.:::...|||| :|...:..|  ::::..|.:|
Human   260 FPRLHFFMPGFAPLTS--RGSQQYRALTVPELTQQMFDSKNMM-AACDPRHGR--YLTVAAIFRG 319

  Fly   328 EVDPSQVHKSLQRIRERKLANFIPWGPASIQVAL----PRSSPYVQSAHKVSGLMMANHTGISSL 388
            .:...:|.:.:..::.:..:.|:.|.|.:::.|:    ||..       |:|...:.|.|.|..|
Human   320 RMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGL-------KMSATFIGNSTAIQEL 377

  Fly   389 FKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYE 437
            |||...|:..:.:|.|||..:..|.|.:.:.||   |...::.||.||:
Human   378 FKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTE---AESNMNDLVSEYQ 423

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.