Protein Alignment gammaTub37C and Tube1

DIOPT Version :10

• Sequence 1: NP_476922.1
• Gene: gammaTub37C / 35199
• FlyBaseID: FBgn0010097
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_082282.1
• Gene: Tube1 / 71924
• MGIID: 1919174
• Length: 475
• Species: Mus musculus
• Alignment Length: 509
• Identity: 135/509 - (26%)
• Similarity: 248/509 - (48%)
• Gaps: 95/509 - (18%)

  Fly     3 SEIITLQLGQCGNQIGFEFWKRLCLEH-GISPDGVLEDFATDGQDRKDVFFYQAD-----DNHYI 61
            ::.:.:|:||||||||..||.....|| .::..|:.:|..:.       ||...|     |...|
Mouse     2 TQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDDAISS-------FFRNVDTRAVGDGGSI 59

  Fly    62 ---------PRAVLIDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASGFSQ-GEKVQE 116
                     .||||||:|..|:|.|:..|...:::.:.:....  .|:|||||.|... |...:|
Mouse    60 SKGRISSLKARAVLIDMEEGVVNEILQGPLRDVFDSKQLITDI--SGSGNNWAVGHKVFGCLYRE 122

  Fly   117 EVFDILDREADGSDSLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDV 181
            ::.:.|.:.|:..|.|:.|.:.||:.||||||:|:::|:.|.:.||:......:|:|:.::  ||
Mouse   123 QILEKLRKSAEQCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTAVYPSSED--DV 185

  Fly   182 VVQPYNSILTLKRLTKCADSVVVLDNTAL---------------------------NRIATERLH 219
            :..||||:|.:|.|.:.||.|:.:||.:|                           :.:...:.|
Mouse   186 ITSPYNSMLAMKELNEHADCVLPIDNQSLFDIISKIDLVVNSGKLGSAVKPKSLITSNMGAVKKH 250

  Fly   220 IQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASLIPTPQLHFLMTGYTPLMSDCETKT 284
            .:.| |..:||:|:.::...|::.|:...:|.:|..::.:|:|.|:||:|::..|||.:..:...
Mouse   251 HKKP-FDAMNNIVANLLLSLTSSARFEGSLNMDLNEISMNLVPFPKLHYLVSSLTPLYTLADVNI 314

  Fly   285 SVRKTTVLDVM--------RRLLQ--PKNMMVSALTDKQSRQCFVSILNIIQGEVDPSQVHKSLQ 339
            ..|:   ||.|        .:|:|  |::.:            :::...|::|.|..|.:.::::
Mouse   315 PPRR---LDQMFSDAFSKDHQLIQADPRHSL------------YLACALIVRGNVQISDLRRNIE 364

  Fly   340 RIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGLMMANHTGISSLFKRALAQYDKLRKRNA 404
            |:  :....|:.|.....:.:| .|.|.|..:|.:  |.:||:|.:...|.....::.:|.|:.|
Mouse   365 RL--KPALQFVSWNQEGWKTSL-CSVPPVGHSHSL--LALANNTCVKPTFMELRERFTRLYKKKA 424

  Fly   405 FLDNFRR-ESMFQDDLTELDIARDTVDCLVQEY---EAATQI---DYPQWSPAV 451
            .|.::.: :.|.:...||   |..::..|:|||   :|...:   |.|:.|.|:
Mouse   425 HLHHYLQVDGMEESTFTE---AVSSLSALIQEYSDLDATKSLPVPDVPRLSVAL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub37C	NP_476922.1	gamma_tubulin	4..436	CDD:276957	128/485 (26%)
Tube1	NP_082282.1	epsilon_tubulin	2..457	CDD:276959	130/489 (27%)