DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTub37C and Tubg2

DIOPT Version :9

Sequence 1:	NP_001260565.1	Gene:	gammaTub37C / 35199	FlyBaseID:	FBgn0010097	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_038942746.1	Gene:	Tubg2 / 680991	RGDID:	1585798	Length:	477	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	299/394 - (75%)
Similarity:	350/394 - (88%)	Gaps:	1/394 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 QADDNHYIPRAVLIDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASGFSQGEKVQEEV 118
            :|||.||||||||:|||||||::|:.|.|:||||.||::||:||||||||||.|||||||:.|::
  Rat    80 RADDEHYIPRAVLLDLEPRVIHSILNSSYAKLYNPENIYLSEHGGGAGNNWARGFSQGEKIHEDI 144

  Fly   119 FDILDREADGSDSLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVV 183
            |||:||||||||||||||||||||||||||:|||:||||::|:||||:|||||||||||:|||||
  Rat   145 FDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVV 209

  Fly   184 QPYNSILTLKRLTKCADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSY 248
            |||||:|||||||:.||.||||||||||||||:|||||.|:|:|||.|||||||.||||||||.|
  Rat   210 QPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGY 274

  Fly   249 MNNNLIGLTASLIPTPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQ 313
            |||:||||.|||||||:|||||||||||.:| ::..|||||||||||||||||||:|||...|:|
  Rat   275 MNNDLIGLIASLIPTPRLHFLMTGYTPLTTD-QSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQ 338

  Fly   314 SRQCFVSILNIIQGEVDPSQVHKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGLM 378
            :..|:::|||||||||||:|||||||||||||||||||||||||||||.|.|||:.|||:|||||
  Rat   339 TNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLM 403

  Fly   379 MANHTGISSLFKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYEAATQID 443
            |||||.|||||:.:..|||||.||.|||:.||:|.:|:|:..|:|.:|:.|..|:.||.|||:.|
  Rat   404 MANHTSISSLFESSCQQYDKLWKRGAFLEQFRKEDIFKDNFEEMDRSREVVQELIDEYHAATRPD 468

  Fly   444 YPQW 447
            |..|
  Rat   469 YISW 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub37C	NP_001260565.1	PLN00222	1..447	CDD:215108	298/392 (76%)
gammaTub37C	NP_001260565.1	gamma_tubulin	4..436	CDD:276957	291/381 (76%)
Tubg2	XP_038942746.1	gamma_tubulin	81..461	CDD:276957	291/380 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	374	1.000	Domainoid score	I844
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	735	1.000	Inparanoid score	I572
OMA	1	1.010	-	-		QHG53966
OrthoDB	1	1.010	-	-		D267298at33208
OrthoFinder	1	1.000	-	-		FOG0002428
OrthoInspector	1	1.000	-	-		mtm9090
orthoMCL	1	0.900	-	-		OOG6_101897
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1612
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840