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Protein Alignment gammaTub37C and TUBA8

DIOPT Version :10

Sequence 1:	NP_476922.1	Gene:	gammaTub37C / 35199	FlyBaseID:	FBgn0010097	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_061816.1	Gene:	TUBA8 / 51807	HGNCID:	12410	Length:	449	Species:	Homo sapiens

Alignment Length:	448	Identity:	134/448 - (29%)
Similarity:	237/448 - (52%)	Gaps:	31/448 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFAT--DGQDRKDVFFYQADDNHYIPRAVL 66
            |.|::.:||.|.|||...|:..||||||..||..:..|:  :..|....||.:..:..::||||:
Human     3 ECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGKHVPRAVM 67

  Fly    67 IDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSD 130
            |||||.|::.:....|.:|::.|.:...|.  .|.||:|.| ::.|::..:.|.|.:.:..|...
Human    68 IDLEPTVVDEVRAGTYRQLFHPEQLITGKE--DAANNYARGHYTVGKESIDLVLDRIRKLTDACS 130

  Fly   131 SLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRL 195
            .|:||::.||..||||||..|.::||||..:.||....::::| ..::|..||:|||||||....
Human   131 GLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYP-APQVSTAVVEPYNSILTTHTT 194

  Fly   196 TKCADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASL 260
            .:.:|...::||.|:..|....|.|:.||:|.:|.|:|.|:|..|.:||:...:|.:|.....:|
Human   195 LEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNL 259

  Fly   261 IPTPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQC------FV 319
            :|.|::||.:..|.|::|  ..|....:.:|.::.....:|.:.||         :|      ::
Human   260 VPYPRIHFPLVTYAPIIS--AEKAYHEQLSVAEITSSCFEPNSQMV---------KCDPRHGKYM 313

  Fly   320 SILNIIQGEVDPSQVHKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGL-----MM 379
            :...:.:|:|.|..|:.::..|:.::...|:.|.|...:|.:....|.|.....::.:     |:
Human   314 ACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCML 378

  Fly   380 ANHTGISSLFKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYE 437
            :|.|.|:..:.|...::|.:..:.||:..:..|.|.:.:.:|   ||:.:..|.::||
Human   379 SNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE---AREDLAALEKDYE 433

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.