Protein Alignment gammaTub37C and TUBE1

DIOPT Version :10

• Sequence 1: NP_476922.1
• Gene: gammaTub37C / 35199
• FlyBaseID: FBgn0010097
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_057346.1
• Gene: TUBE1 / 51175
• HGNCID: 20775
• Length: 475
• Species: Homo sapiens
• Alignment Length: 496
• Identity: 135/496 - (27%)
• Similarity: 243/496 - (48%)
• Gaps: 94/496 - (18%)

  Fly     3 SEIITLQLGQCGNQIGFEFWKRLCLEH-GISPDGVLEDFATDGQDRKDVFFYQAD-----DNHYI 61
            ::.:.:|:||||||||..||.....|| .::..|:.::..:.       ||...|     |...|
Human     2 TQSVVVQVGQCGNQIGCCFWDLALREHAAVNQKGIYDEAISS-------FFRNVDTRVVGDGGSI 59

  Fly    62 ---------PRAVLIDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASGFSQ-GEKVQE 116
                     .||||||:|..|:|.|:..|...:::.:.:....  .|:|||||.|... |...|:
Human    60 SKGKICSLKARAVLIDMEEGVVNEILQGPLRDVFDTKQLITDI--SGSGNNWAVGHKVFGSLYQD 122

  Fly   117 EVFDILDREADGSDSLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDV 181
            ::.:...:.|:..|.|:.|.:.||:.||||||:|:::|:.|.:.||:......|::|:.::  ||
Human   123 QILEKFRKSAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPEVYRFVTSIYPSGED--DV 185

  Fly   182 VVQPYNSILTLKRLTKCADSVVVLDNTALNRI----------------------------ATERL 218
            :..||||||.:|.|.:.||.|:.:||.:|..|                            |.::.
Human   186 ITSPYNSILAMKELNEHADCVLPIDNQSLFDIISKIDLMVNSGKLGTTVKPKSLVTSSSGALKKQ 250

  Fly   219 HIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASLIPTPQLHFLMTGYTPLMSDCETK 283
            | :.| |..:||:|:.::...|::.|:...:|.:|..::.:|:|.||||:|::..|||.:..:..
Human   251 H-KKP-FDAMNNIVANLLLNLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYTLTDVN 313

  Fly   284 TSVRKTTVLDVM--------RRLLQ--PKNMMVSALTDKQSRQCFVSILNIIQGEVDPSQVHKSL 338
            ...|:   ||.|        .:||:  ||:.:            :::...:::|.|..|.:.:::
Human   314 IPPRR---LDQMFSDAFSKDHQLLRADPKHSL------------YLACALMVRGNVQISDLRRNI 363

  Fly   339 QRIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGLMMANHTGISSLFKRALAQYDKLRKRN 403
            :|::..  ..|:.|.....:.:| .|.|.|..:|.:  |.:||:|.:...|.....::.:|.|:.
Human   364 ERLKPS--LQFVSWNQEGWKTSL-CSVPPVGHSHSL--LALANNTCVKPTFMELKERFMRLYKKK 423

  Fly   404 AFLDNFRR-ESMFQDDLTELDIARDTVDCLVQEYEAATQID 443
            |.|.::.: |.|.:...||   |..::..|:|||:   |:|
Human   424 AHLHHYLQVEGMEESCFTE---AVSSLSALIQEYD---QLD 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub37C	NP_476922.1	gamma_tubulin	4..436	CDD:276957	131/486 (27%)
TUBE1	NP_057346.1	epsilon_tubulin	2..457	CDD:276959	133/493 (27%)