Protein Alignment gammaTub37C and TUBD1

DIOPT Version :9

• Sequence 1: NP_001260565.1
• Gene: gammaTub37C / 35199
• FlyBaseID: FBgn0010097
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_057345.2
• Gene: TUBD1 / 51174
• HGNCID: 16811
• Length: 453
• Species: Homo sapiens
• Alignment Length: 461
• Identity: 134/461 - (29%)
• Similarity: 213/461 - (46%)
• Gaps: 79/461 - (17%)

  Fly     5 IITLQLGQCGNQIGFEFWKRLCLEHGISPDGVL-----EDFATDGQDRKDVFFYQADDNHYIPRA 64
            |:|:||||||||||||.:..| |....|..|:.     |.:....::|   ||.:.::...|.||
Human     3 IVTVQLGQCGNQIGFEVFDAL-LSDSHSSQGLCSMRENEAYQASCKER---FFSEEENGVPIARA 63

  Fly    65 VLIDLEPRVINNIMTSPYSK---LYNQENVFLSKHGGGAGNNWASGFS-QGEKVQEEVFDILDRE 125
            ||:|:||:|||.:::.....   .|.|...|..|.  |:|||||.|:| .|.:.:|.:.:|:.:|
Human    64 VLVDMEPKVINQMLSKAAQSGQWKYGQHACFCQKQ--GSGNNWAYGYSVHGPRHEESIMNIIRKE 126

  Fly   126 ADGSDSLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSIL 190
            .:..||..||.:..|:|||||||:|::|.:.|.:::...|.....::|.  ...:|:||.|||||
Human   127 VEKCDSFSGFFIIMSMAGGTGSGLGAFVTQNLEDQYSNSLKMNQIIWPY--GTGEVIVQNYNSIL 189

  Fly   191 TLKRLTKCADSVVVLDNTALNRIATERLHIQTPTFTQINN-LVSTIMSLSTTTLRYPS---YMNN 251
            ||..|.:.:|::::.:|.|:::|..:.::|:..:|:.||. |...:.|:...|....|   |..|
Human   190 TLSHLYRSSDALLLHENDAIHKICAKLMNIKQISFSDINQVLAHQLGSVFQPTYSAESSFHYRRN 254

  Fly   252 NLIGLTASLIPTPQLHFLMTGYTPLMSDCETKTSVRKTT-----VLDVMRRLLQPKNMM------ 305
            .|..|...|:|.|:...|.....|.||:    .|:..||     :|..:|::|.....|
Human   255 PLGDLMEHLVPHPEFKMLSVRNIPHMSE----NSLAYTTFTWAGLLKHLRQMLISNAKMEEGIDR 315

  Fly   306 -----------VSALTDKQSRQCFVSILNI------------IQGEVDPSQVHKSLQRIRERKLA 347
                       :|.::..:......||.|:            ::|..||:.....|:.:..
Human   316 HVWPPLSGLPPLSKMSLNKDLHFNTSIANLVILRGKDVQSADVEGFKDPALYTSWLKPVNA---- 376

  Fly   348 NFIPWGPASIQVALPRSSPYVQSAHKVSGL--------MMANHTGISSLFKRALAQYDKLR-KRN 403
             |..|   ..|.|.   |.|.:||..||..        |:..........|..:.||.|.. :..
Human   377 -FNVW---KTQRAF---SKYEKSAVLVSNSQFLVKPLDMIVGKAWNMFASKAYIHQYTKFGIEEE 434

  Fly   404 AFLDNF 409
            .|||:|
Human   435 DFLDSF 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub37C	NP_001260565.1	PLN00222	1..447	CDD:215108	134/461 (29%)
		gamma_tubulin	4..436	CDD:276957	134/461 (29%)
TUBD1	NP_057345.2	delta_zeta_tubulin-like	2..452	CDD:276958	134/461 (29%)
		Tubulin	2..213	CDD:278518	80/217 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3728
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.760