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Protein Alignment gammaTub37C and Tuba3a

DIOPT Version :10

Sequence 1:	NP_476922.1	Gene:	gammaTub37C / 35199	FlyBaseID:	FBgn0010097	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001035097.1	Gene:	Tuba3a / 500319	RGDID:	1565719	Length:	450	Species:	Rattus norvegicus

Alignment Length:	442	Identity:	137/442 - (30%)
Similarity:	239/442 - (54%)	Gaps:	19/442 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFAT--DGQDRKDVFFYQADDNHYIPRAVL 66
            |.|::.:||.|.|||...|:..||||||.|||.:....|  .|.|..:.||.:.....::||||.
  Rat     3 ECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVF 67

  Fly    67 IDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSD 130
            :||||.|::.:.|..|.:|::.|.:...|.  .|.||:|.| ::.|:::.:.|.|.:.:.||...
  Rat    68 VDLEPTVVDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIVDLVLDRIRKLADLCT 130

  Fly   131 SLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRL 195
            .|:||::.||..||||||..|.::||||..:.||....::::| ..::|..||:|||||||....
  Rat   131 GLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYP-APQVSTAVVEPYNSILTTHTT 194

  Fly   196 TKCADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASL 260
            .:.:|...::||.|:..|....|.|:.||:|.:|.|:..|:|..|.:||:...:|.:|.....:|
  Rat   195 LEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259

  Fly   261 IPTPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNII 325
            :|.|::||.:..|.|::|  ..|....:.:|.::.....:|.|.||..  |.:..: :::...:.
  Rat   260 VPYPRIHFPLATYAPVIS--AEKAYHEQLSVAEITNACFEPANQMVKC--DPRHGK-YMACCMLY 319

  Fly   326 QGEVDPSQVHKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGL-----MMANHTGI 385
            :|:|.|..|:.::..|:.::...|:.|.|...:|.:....|.|.....::.:     |::|.|.|
  Rat   320 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAI 384

  Fly   386 SSLFKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYE 437
            :..:.|...::|.:..:.||:..:..|.|.:.:.:|   ||:.:..|.::||
  Rat   385 AEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE---AREDLAALEKDYE 433

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.