Protein Alignment gammaTub37C and TUBB8

DIOPT Version :9

• Sequence 1: NP_001260565.1
• Gene: gammaTub37C / 35199
• FlyBaseID: FBgn0010097
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_817124.1
• Gene: TUBB8 / 347688
• HGNCID: 20773
• Length: 444
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 154/439 - (35%)
• Similarity: 257/439 - (58%)
• Gaps: 23/439 - (5%)

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFATDGQDRKDVFFYQADDNHYIPRAVLID 68
            ||:..|:||||||||.:||:.:..||.|...|.....:....:|.:|::.:|....|:|||||:|
Human     3 EIVLTQIGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVYYNEASGGRYVPRAVLVD 67

  Fly    69 LEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSDSL 132
            |||..::::.:.|:.:::..:|....:  .|||||||.| :::|.::.|.|.|::.:||:..|.|
Human    68 LEPGTMDSVRSGPFGQVFRPDNFIFGQ--CGAGNNWAKGHYTEGAELMESVMDVVRKEAESCDCL 130

  Fly   133 EGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRLTK 197
            :||.|.||:.||||||||:.:|.::.|.:|.::|.|:|:.|: .::||.||:|||:.|::.:|.:
Human   131 QGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRIINTFSILPS-PKVSDTVVEPYNATLSVHQLIE 194

  Fly   198 CADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASLIP 262
            .||....:||.||..|.::.|.:.|||:..:|:|||..||..||.||:|..:|.:|..|..:::|
Human   195 NADETFCIDNEALYDICSKTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 259

  Fly   263 TPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNIIQG 327
            .|:|||.|.|:.||.|  ......|..||.::.:::...|||| :|...:..|  :::...|.:|
Human   260 FPRLHFFMPGFAPLTS--RGSQQYRALTVAELTQQMFDAKNMM-AACDPRHGR--YLTAAAIFRG 319

  Fly   328 EVDPSQVHKSLQRIRERKLANFIPWGPASIQVAL----PRSSPYVQSAHKVSGLMMANHTGISSL 388
            .:...:|.:.:..|:::..:.|..|.|.:::.|:    ||..       |:|...:.|:|.|..|
Human   320 RMPMREVDEQMFNIQDKNSSYFADWLPNNVKTAVCDIPPRGL-------KMSATFIGNNTAIQEL 377

  Fly   389 FKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYE 437
            |||...|:..:.:|.|||..:..|.|.:.:.||   |...::.||.||:
Human   378 FKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTE---AESNMNDLVSEYQ 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub37C	NP_001260565.1	PLN00222	1..447	CDD:215108	154/439 (35%)
		gamma_tubulin	4..436	CDD:276957	152/436 (35%)
TUBB8	NP_817124.1	PTZ00010	1..427	CDD:240228	154/439 (35%)
		beta_tubulin	2..426	CDD:276956	154/439 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..444		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810