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Protein Alignment gammaTub37C and TUBB8B

DIOPT Version :10

Sequence 1:	NP_476922.1	Gene:	gammaTub37C / 35199	FlyBaseID:	FBgn0010097	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001345618.1	Gene:	TUBB8B / 260334	HGNCID:	24983	Length:	444	Species:	Homo sapiens

Alignment Length:	439	Identity:	153/439 - (34%)
Similarity:	254/439 - (57%)	Gaps:	23/439 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFATDGQDRKDVFFYQADDNHYIPRAVLID 68
            ||:..|.||||||||.:||:.:..||.|...|.....:....:|.:|..::|....|:|||||:|
Human     3 EIVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYVPRAVLVD 67

  Fly    69 LEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSDSL 132
            |||..::::.:.|:.:::..:| |:|.. .|||||||.| :::|.::.|.|.|::.:||:..|.|
Human    68 LEPGTMDSVHSGPFGQVFRPDN-FISGQ-CGAGNNWAKGRYTEGAELTESVMDVVRKEAESCDCL 130

  Fly   133 EGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRLTK 197
            :||.|.||:.||||||||:.::.::.|.:|.::|.|:|:.|: .::||.||:|||:.|::.:|.:
Human   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIINTFSILPS-PKVSDTVVEPYNATLSVHQLIE 194

  Fly   198 CADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASLIP 262
            .||....:||.||..|.:..|.:.|||:..:|:|||..||..||.||:|..:|.:|..|..:::|
Human   195 NADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 259

  Fly   263 TPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNIIQG 327
            .|:|||.|.|:.||.|  ......|..||.::.:::...||||  |..|.: ..|::::..|.:|
Human   260 FPRLHFFMPGFAPLTS--RGSQQYRALTVAELTQQMFDAKNMM--AACDPR-HGCYLTVAAIFRG 319

  Fly   328 EVDPSQVHKSLQRIRERKLANFIPWGPASIQVAL----PRSSPYVQSAHKVSGLMMANHTGISSL 388
            .:...:|.:.:..|:::..:.|..|.|.:::.|:    ||..       |:|...:.|:..|..|
Human   320 RMPMREVDEQMFNIQDKNSSYFADWFPDNVKTAVCDIPPRGL-------KMSATFIGNNAAIQEL 377

  Fly   389 FKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYE 437
            |.....|:..:.:|.|||..:..|.|.:.:.||   |...::.||.||:
Human   378 FTCVSEQFTAMFRRKAFLHWYTGEGMDEMEFTE---AESNMNDLVSEYQ 423

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.